16
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2354 | UNC 0631 | UNC0631 | Histone Methyltransferase |
UNC 0631 is a effectvie histone methyltransferase G9a inhibitor (IC50=4 nM). | |||
TQ0232 | UNC0646 | UNC 0646 | Histone Methyltransferase |
UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646(UNC 0646) potently blocks G9a/GLP methyltransferase activity in cells ... | |||
T4820 | Maleimide | 2,5-Pyrroledione | Others |
Maleimide (2,5-Pyrroledione) (2,5-Pyrroledone) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its b... | |||
T3229 | Cytochalasin D | ATPase , p38 MAPK , Calcium Channel , Akt , PI3K | |
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec... | |||
TP2505L | LAH4 acetate | KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base) | Antibacterial |
LAH4 acetate is the α-helical structure of the designed amphoteric peptide antibiotic, which is capable of complexing DNA, associating with the cell surface membrane and wrapped in the endosome, which is destroyed with t... | |||
T11797 | L-690488 | Others | |
L-690488 has more effective cell penetration than L-690330. L-690488 is a prodrug of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor. | |||
T61701 | SHP2-IN-9 | ||
SHP2-IN-9 is a potent inhibitor (IC50 = 1.174 μM) specifically targeting the SHP2 protein, displaying improved penetration across the blood-brain barrier. It exhibits a remarkable 85-fold selectivity for SHP2 over SHP1. ... | |||
T60970 | Caprochlorone | ||
Caprochlorone exhibits antiviral activity against orthopoxvirus that decreases the influenza virus titers in infected-mice lungs. Caprochlorone can inhibit cell penetration by virus as well as delays newly formed virus r... | |||
T17454 | ATP-polyamine-biotin | Others | |
ATP-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM. ATP-polyamine-biotin i... | |||
T75762 | LAH4 TFA | ||
LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, demonstrates potent antimicrobial, nucleic acid transfection, and cell penetration capabilities, alongside high plasmid DNA delivery capacities. It... | |||
T68547 | SNJ-1945 | ||
SNJ-1945 is a calpain inhibitor with more favorable retinal penetration, high oral bioavailability, and long half-life. SNJ1945 rescued defective function in lissencephaly. SNJ-1945 protects SH-SY5Y cells against MPP(+) ... | |||
T61388 | HAChE/Aβ1-42-IN-1 | ||
Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and excellent brain-blood barrier (BBB) penetration with a broad sa... | |||
T81526 | Pegsebrenatide | NLY01 | |
Pegsebrenatide (NLY01), a long-acting GLP-1R agonist, exhibits an extended half-life and favorable blood-brain barrier penetration. It impedes A1 astrocyte transformation, mitigates dopaminergic cell death, and ameliorat... | |||
T71577 | KOS-1584 | ||
KOS-1584 is a second-generation epothilone with potential antineoplastic activity. Epothilone KOS-1584 binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which m... | |||
T82010 | JDB175 | BTK | |
JDB175, a selective BTK inhibitor with oral bioavailability, demonstrates excellent penetration through the blood-brain barrier. It exhibits potent activity against central nervous system lymphoma in a mouse model, with ... | |||
T68860 | Iso-Fludelone | ||
Iso-Fludelone is the third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules agai... |