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Search Results for " antimigratory "

8

Compounds

Cat No. Product Name Synonyms Targets
T8976 PD-089828 EGFR , FGFR , PDGFR , Src
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...
T9945 MNK8  3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione STAT
MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].
T11154L EG01377 2HCl EG01377 2HCl(2227996-00-9 Free base) Complement System
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angioge...
T5S0055 Chelidonine Helidonine,Khelidonin,Stylophorin Apoptosis , Others , Influenza Virus
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...
T11154 EG01377 Others
EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP...
T83211 Ac2-12 TFA
Ac2-12 TFA, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibits neutrophil extravasation and demonstrates antimigratory effects by attenuating the recruitment of neutrophils in experimental models of inflammation [1]...
T83523 (S)-(-)-MRJF22
(S)-(-)-MRJF22, a haloperidol metabolite II valproate ester, demonstrates potent antimigratory effects in both endothelial and tumor cells, and is considered a promising multifunctional agent in the treatment of uveal me...
T72276 EG01377 dihydrochloride
EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) , with a K d of 1.32 μM, and IC 50 s of 609 nM for both NRP1-a1 and NRP1-b1 . EG01377 dihydrochloride has antiangiogenic, a...
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