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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14046 | Anandamide | (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide | Cannabinoid Receptor , Endogenous Metabolite |
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy... | |||
T8425 | Linoleoyl Ethanolamide | TRP/TRPV Channel | |
Linoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in an independent manner. | |||
T15802 | LY2183240 | FAAH , Autophagy | |
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM). | |||
T5357 | ARN272 | ARN 272 | FAAH |
ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM). | |||
T12302 | OMDM-1 | (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide | Endogenous Metabolite |
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM. | |||
T12307 | OMDM-6 | Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM. | |||
T8646 | URB937 | FAAH | |
URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM). | |||
T15948 | MAFP | Methyl Arachidonyl Fluorophosphonate | Phospholipase |
MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase. MAFP is an active-site directed and irreversible inhibitor of cPLA2 and iPLA2. | |||
T12306 | OMDM-5 | Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM). | |||
T3354 | BIA 10-2474 | BIA10-2474 | FAAH , Autophagy |
BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o... | |||
T12305 | OMDM-4 | Others | |
OMDM-4 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 17.7 μM). | |||
T12303 | OMDM-2 | Others | |
OMDM-2 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 3.0 μM). | |||
T12304 | OMDM-3 | Others | |
OMDM-3 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 16.6 μM). | |||
T23503 | VDM 11 | Others | |
anandamide transport inhibitor | |||
T23006 | MM-22 | Others | |
biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide | |||
T23100 | O-2093 | Others | |
anandamide uptake inhibitor | |||
T38389 | Prostaglandin D2 Ethanolamide | Prostaglandin D2 Ethanolamide | |
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The ... | |||
T69577 | LEI-301 | ||
LEI-301 is a novel potent inhibitor for the PLAAT family members, reducing the NAE levels, including anandamide, in cells overexpressing PLAAT2 or PLAAT5. | |||
T27681 | JNJ-40355003 | JNJ40355003 | |
JNJ-40355003, a potent and selective fatty acid amide hydrolase (FAAH) inhibitor, elevates the plasma levels of three fatty acid amides: anandamide, oleoyl ethanolamide, and palmitoyl ethanolamide, in the rat, dog, and c... | |||
T37785 | 1-Palmitoyl-2-linoleoyl PE | ||
Phosphatidylethanolamines are important components of cell membranes and biochemical pathways of fatty acid synthesis. 1-Palmitoyl-2-linoleoyl PE (PLPE) is one of the many phosphatidylethanolamines that may be present in... |