Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OMDM-4 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 17.7 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | OMDM-4 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 17.7 μM). |
Targets&IC50 | Anandamide cellular uptake:ki:17.7 μM |
In vitro | OMDM-4 is anovel potent and selective inhibitors of ACU?and one 'hybrid' agonist of CB(1) and VR1 receptors (OMDM-6).?Unlike other compounds of the same type, OMDM-1, OMDM-2, and OMDM-6 were very stable to enzymatic hydrolysis by rat brain homogenates.OMDM-4 shows poor affinity for either CB1 (Ki=12.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively;?OMDM-4 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50≥10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1]. |
Molecular Weight | 453.66 |
Formula | C29H43NO3 |
CAS No. | 616884-65-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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OMDM-4 616884-65-2 Others OMDM4 OMDM 4 inhibitor inhibit