Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OMDM-2 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 3.0 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 48.00 | |
5 mg | 35 days | $ 195.00 | |
10 mg | 35 days | $ 345.00 | |
50 mg | 35 days | $ 1,480.00 |
Description | OMDM-2 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor(Ki of 3.0 μM). |
Targets&IC50 | Anandamide cellular uptake:ki:3.0 μM |
In vitro | OMDM-2 is anovel potent and selective inhibitors of ACU?and one 'hybrid' agonist of CB(1) and VR1 receptors (OMDM-6).?Unlike other compounds of the same type, OMDM-1, OMDM-2, and OMDM-6 were very stable to enzymatic hydrolysis by rat brain homogenates.OMDM-2 shows poor affinity for either CB1 (Ki=12.1 μM) or CB2 (Ki>10 μM) receptors in rat brain and spleen membranes, respectively;?OMDM-2 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC50≥10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (Ki>50 μM)[1]. |
Molecular Weight | 431.65 |
Formula | C27H45NO3 |
CAS No. | 616884-63-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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OMDM-2 616884-63-0 Others OMDM 2 OMDM2 inhibitor inhibit