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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T73579 | YM-1 | ||
YM-1, a stable and soluble analog of MKT-077, is an orally active inhibitor of Hsp70 that induces cell death in HeLa cells and elevates the levels of p53 and p21 proteins [1] [2]. | |||
T35261 | YM 26567-1 | YM-26567-1,YM26567-1 | |
YM 26567-1 is a biochemical. | |||
T35256 | YM 16151-1 | YM-16151,YM16151 | |
YM 16151-1 is a biochemical. | |||
T8436 | Minodronic acid | Phosphonicacid,(1-hydroxy-2-imidazo(1,2-a)pyridin-3-ylethylidene)bis-,ONO-5920,YM-529 | Apoptosis , P2X Receptor |
Minodronic acid(YM-529) is a P2X2/3 receptor antagonist with anticancer activity, directly or indirectly inhibiting the proliferation of cancer cells and inducing apoptosis. Minodronic acid has been shown to inhibit the ... | |||
T7417 | Avatrombopag | YM477,AKR-501,E5501 | Thrombin , Thrombopoietin Receptor |
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production. | |||
T7550 | Barnidipine | YM-09730-5(Free base),Mepirodipine | Calcium Channel |
Barnidipine (YM-09730-5(Free base)) is a calcium channel blocker. | |||
T29183 | YM-430 | YM-15430,YM-15430-1,YM-154301,YM-15430-2,YM430,YM-15430-3 | |
YM-430 is a β1 adrenergic receptor antagonist and a calcium channel antagonist. YM430 could be both an antianginal and antihypertensive agent. YM430 (10(-8)-10(-6) M) inhibited 3,4-diaminopyridine-induced rhythmic contra... | |||
T19629 | Indeloxazine hydrochloride | CI-874l,Indeloxazine HCl,YM 08054-1,Indeloxazine,CI 874,CI874l | |
Indeloxazine HCl acts as a serotonin releasing agent, norepinephrine reuptake inhibitor, and NMDA receptor antagonist. Indeloxazine hydrochloride is an antidepressant and cerebral activator. It has been found to enhance ... | |||
T8435 | YM90K | YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)- | GluR , iGluR |
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor. | |||
T29182 | YM-358 potassium hydrate | YM-358,YM358,YM 358 | |
YM-358 potassium hydrate is an orally active and long-lasting antagonist of angiotensin type 1 receptor. | |||
T69489 | YM-202074 | ||
YM-202074 is a high affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM-202074 binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. It inhibits mGlu1-mediated inositol pho... | |||
T21834 | YM-155 hydrochloride | ||
Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1]. | |||
T80752 | YM-08 | Sirtuin | |
YM-08 (Compound 7a), a brain-penetrant SIRT2 inhibitor, exhibits an IC50 of 19.9 μM. Additionally, it acts as an inhibitor of Hsp70 [1]. | |||
T76979 | Tadocizumab | ||
Tadocizumab (C4G1; YM-337), a humanized monoclonal antibody targeting integrin αIIbβ3, exhibits antiplatelet and antithrombotic properties. It is utilized in research into cardiovascular diseases [1] [2]. |