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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9227 | Val-Ala-PAB | Others | |
Val-Ala-PAB is a building block in the synthesis of Tesirine (a.k.a. SG3249), a clinical antibody-drug conjugate pyrrolobenzodiazepine dimer payload. Reagent in the preparation of pyrrolobenzodiazepine dimers and their a... | |||
T18868 | Val-Cit | Others | |
Val-Cit is a cleavable ADC linker. Val-Cit is used in the synthesis of antibody-drug conjugates (ADCs). | |||
T4289 | Mc-Val-Ala-PAB | Mc-Val-Ala-PAB | Others , AChR |
Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC). | |||
T4286 | Fmoc-Val-Ala-PAB-OH | Fmoc-Val-Ala-PAB | Others , AChR |
Fmoc-Val-Ala-PAB-OH (Fmoc-Val-Ala-PAB) is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD peptidomimetic-paclitaxel conjugates... | |||
T4678 | Fmoc-Val-Cit-PAB | Others | |
Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC). | |||
TN6675 | Cyclo(Pro-Val) | Cyclo(prolylvalyl) | Antibacterial , Antifungal |
Cyclo(Pro-Val) (Cyclo(prolylvalyl)) is obtained from the marine fungus and shows moderate antifungal and weak antitumor activities. Cyclo(Pro-Val) inhibits the growth of Bacillus subtilis with MIC of 0.8 g/L. | |||
T17693 | Boc-Val-Cit-PAB | Others | |
Boc-Val-Cit-PAB is a cleavable ADC linker. Boc-Val-Cit-PAB used in the synthesis of antibody-drug conjugates (ADCs). | |||
T17213 | Val-cit-PAB-OH | Others | |
Val-cit-PAB-OH is an ADC linker that is cleavable. | |||
T18867 | Val-Cit-PAB-MMAE | ||
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat... | |||
T17212 | VAL-083 | Dianhydrogalactitol,Dianhydrodulcitol | DNA Alkylator/Crosslinker , DNA Alkylation |
VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity. | |||
T17691 | Boc-Val-Cit-OH | Others | |
Boc-Val-Cit-OH is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T7354 | H-Val-Pro-Pro-OH | RAAS | |
H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM). | |||
T17983 | Fmoc-Val-Cit-PAB-MMAE | Others | |
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. | |||
T18318 | MC-Val-Ala-PAB-PNP | Others | |
MC-Val-Ala-PAB-PNP is a cleavable ADC linker. MC-Val-Ala-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs). | |||
T17692 | Boc-Val-Cit-PAB-PNP | Others | |
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T7767 | FMoc-Val-Cit-PAB-PNP | Others | |
Fmoc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). | |||
T18321 | Mc-Val-Cit-PAB-Cl | Others | |
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC5... | |||
T18267 | Mal-PEG1-Val-Cit-OH | Others | |
Mal-PEG1-Val-Cit-OH is a cleavable one-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T5149 | MC-Val-Cit-PAB | Others , AChR | |
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker. | |||
T19350 | H-Val-Ala-OH | Valyl-alanine | Endogenous Metabolite |
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. It has a role as a metabolite. H-Val-Ala-OH is a dipeptide formed from L-Valine and L-Alanine residues. |