Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 119.00 | |
5 mg | In stock | $ 297.00 | |
10 mg | In stock | $ 478.00 | |
25 mg | In stock | $ 898.00 | |
50 mg | In stock | $ 1,230.00 | |
100 mg | In stock | $ 1,660.00 |
Description | Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively. |
Molecular Weight | 591.1 |
Formula | C28H39ClN6O6 |
CAS No. | 1639351-92-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Mc-Val-Cit-PAB-Cl 1639351-92-0 Others Mc Val Cit PAB Cl Antibody-drug conjugates linkers McValCitPABCl ADC Linkers inhibit Inhibitor inhibitor