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Val-cit-PAB-OH

Name: Val-cit-PAB-OH
Brand: TargetMol
SKU: T17213
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T17213Cas No. 159857-79-1

Val-cit-PAB-OH is an ADC linker that is cleavable.

Val-cit-PAB-OH

🥰Excellent

Purity: 99.11%

Catalog No. T17213Cas No. 159857-79-1

Val-cit-PAB-OH is an ADC linker that is cleavable.

Pack Size	Price	Availability	Quantity
100 mg	$29	In Stock

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Batch Information

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Purity:99.11%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description

Val-cit-PAB-OH is an ADC linker that is cleavable.

Chemical Properties

Molecular Weight	379.45
Formula	C₁₈H₂₉N₅O₄
Cas No.	159857-79-1
Smiles	CC(C)[C@H](N)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
Relative Density.	1.243 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (263.54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6354 mL	13.1770 mL	26.3539 mL	131.7697 mL
5 mM	0.5271 mL	2.6354 mL	5.2708 mL	26.3539 mL
10 mM	0.2635 mL	1.3177 mL	2.6354 mL	13.1770 mL
20 mM	0.1318 mL	0.6588 mL	1.3177 mL	6.5885 mL
50 mM	0.0527 mL	0.2635 mL	0.5271 mL	2.6354 mL
100 mM	0.0264 mL	0.1318 mL	0.2635 mL	1.3177 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc