v1a — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T126501	Xanthone V1a
	Xanthone V1a is a useful organic compound for research related to life sciences and the catalog number is T126501.
T11857	LIT-001		Oxytocin Receptor
	LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM.		Oxytocin Receptor
T80160	ω-Hexatoxin-Hv1a	ω-ACTX-Hv1,ω-Atracotoxin-HV1	Calcium Channel
	ω-Hexatoxin-Hv1a, a neurotoxin extracted from the venom of the spider Hadronyche versuta, inhibits voltage-gated calcium channels [1] [2].		Calcium Channel
T6453	Conivaptan hydrochloride	Vaprisol,Conivaptan HCl,YM 087	Vasopressin Receptor
	Conivaptan hydrochloride (Vaprisol) is an orally active vasopressin V2 and V1A receptor antagonist, used in the therapy of hypervolemic hyponatremia and euvolemic.		Vasopressin Receptor
T4141	RG7713	RO 5028442	Vasopressin Receptor
	RG7713 (RO 5028442) has been used in trials studying Autistic Disorder.		Vasopressin Receptor
TP2082L	D[Cha4]-AVP acetate(500170-27-4 free base)		Vasopressin Receptor
	d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secre...		Vasopressin Receptor
T14494	Balovaptan	RG7314	Vasopressin Receptor
	Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors. It is used for the research of autism.		Vasopressin Receptor
T16934	SRX246		Others
	SRX246 has no interaction at V1b and V2 receptors. SRX246 shows negligible binding at 64 other receptors classes, including 35 G-proteincoupled receptors. SRX246 is a potent and CNS-penetrant vasopressin 1a (V1a) recepto...		Others
T17251	VNA-932	WAY-VNA 932	Others
	VNA-932 is an agonist of the vasopressin V2-receptor (IC50: 80.3 nM and 778 nM in human-V2 binding and V1a binding assay).		Others
T15682	L-371,257		Oxytocin Receptor , Vasopressin Receptor
	L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.		Oxytocin Receptor , Vasopressin Receptor
T23393	SR 49059		Others
	vasopressin V1A receptor antagonist		Others
T24625	PF-184563	PF184563,PF 184563
	PF-184563 is an effective and selective non-peptidic V1a receptor antagonist.
T28745	Selepressin	FE 202158,FE202158
	Selepressin, an analog of vasopressin, is a potent, selective vasopressin V1a receptor agonist.
T28629	RWJ 676070	RWJ676070,RWJ-676070
	RWJ 676070 is an antagonist of vasopressin V1A/V2 receptor.
T28854	SRX 251	SRX-251,SRX251
	SRX 251, a vasopressin V1a receptor antagonist, is used potentially for the treatment of primary dysmenorrhea.
T29177	YM 218	YM218,YM-218
	YM 218 is a novel, potent, selective antagonist of nonpeptide vasopressin V1A receptor.
T25577	Khusimol
	Khusimol is a vasopressin V1a receptors non-peptide ligand that acts by inhibiting the binding of vasopressin.
T29178	YM 471	YM-471,YM471
	YM 471 is a non-peptide arginine vasopressin (AVP) V1A and V2 receptor antagonist with oral activity.
T80137	(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin	d(CH2)5[Tyr(Me)2, Dab5]AVP	Vasopressin Receptor
	(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].		Vasopressin Receptor
T24370	L-368899 free base	L 368899,L 368,899,L368,899,L-368899,L368899,L-368,899
	L-368899 is a non-peptide and orally active antagonist of oxytocin receptor (IC50: 8.9 nM). It displays 40-fold selectivity over vasopressin V1a and V2 receptors (IC50: 370 and 570 nM respectively).