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Search Results for " v-8 "

Targets

14

Compounds

2

Natural Products

17

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6289 Dovitinib TKI258,CHIR-258 VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...
T6479 Dovitinib lactate hydrate Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258 VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...
TP1913L1 BA 1 acetate(183241-31-8 free base) Bombesin Receptor
BA 1 acetate is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 ...
T6193 Dovitinib Dilactic Acid Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid VEGFR , FGFR , FLT , c-Kit
Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FG...
T70368 SF0166
SF0166 is a potent, selective antagonist of α v β 3, demonstrating IC 50 values of 0.6 nM for α v β 3, 8 nM for α v β 6, and 13 nM for α v β 8. It effectively inhibits cellular adhesion to vitronectin in human, rat, rabb...
T125413 4'-O-Methylabyssinone V
4'-O-Methylabyssinone V is a useful organic compound for research related to life sciences. The catalog number is T125413 and the CAS number is 201480-12-8.
T80451 Ceratotoxin-2 CcoTx2,β-TRTX-cm1b Sodium Channel
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel inhibitor, demonstrating half maximal inhibitory concentrations (IC50) of 8 nM for Na v 1.2/β 1 and 88 nM for Na v 1.3/β 1 [1].
T37837 2-Methylhexacosane
2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone.1,2It has been found in the cuticle ofM. dasystomusfemales, but not males, where it contributes to the mating behavior of males, as well as inD. melan...
T36516 RC574 RC574
RC574 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol .1It inhibits glutamate-induced cell death in HT22 cells (IC50= 276.2 nM) and mouse primary cortical neurons...
T37847 Zonisamide-13C2,15N Zonisamide-13C2,15N
Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels ...
T36515 RC363
RC363 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol .1It reduces 2,2-diphenyl-1-picrylhydrazyl radicals by approximately 40% in a cell-free assay when used at a...
T36978 AS-99 TFA
AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and different...
T36977 AS-99 free base
AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, ...
T35881 Resolvin E2
Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-...
Cat No. Product Name Synonyms Targets
TN5261 Withanoside V Others
Withanoside V is a natural product for research related to life sciences. The catalog number is TN5261 and the CAS number is 256520-90-8.
T36000 3-Hydroxyterphenyllin
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05717 Integrin alpha V beta 8 Protein, Human, Recombinant (His) Human HEK293 Cells
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto...
TMPY-03225 VSIG8 Protein, Human, Recombinant (hFc) Human HEK293 Cells
V-set and immunoglobulin domain containing 8 (VSIG8) is essential in hair cycle, oral mucosa, and the nail matrix. Moreover, VSIG8 also has an important role in proper epithelial differentiation and function in the upper...
TMPJ-00263 VSIG8 Protein, Human, Recombinant (His) Human HEK293 Cells
V-set and immunoglobulin domain-containing protein 8(VSIG8) is a single-pass type I membrane protein.The human VSIG8 cDNA encodes 414 amino acids (aa) including a 21 aa signal sequence, a 242 aa extracellular domain (ECD...
TMPJ-01180 VSIG8 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
V-set and immunoglobulin domain-containing protein 8(VSIG8) is a single-pass type I membrane protein.The mouse VSIG8 cDNA encodes 417 amino acids (aa) including a 21 aa signal sequence, a 241 aa extracellular domain (ECD...
TMPY-02243 IGSF3 Protein, Human, Recombinant (His) Human HEK293 Cells
Immunoglobulin superfamily member 3 (IGSF3), also known as Glu-Trp-Ile EWI motif-containing protein 3, IgSF3 and EWI-3 and IGSF3, is a single-pass type I membrane protein that belongs to the EWI subfamily of the Ig super...
TMPH-02187 Tenascin Protein, Human, Recombinant (E. coli, His) Human E. coli
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown o...
TMPH-00375 IL-8/CXCL8 Protein, Chicken, Recombinant (His) Chicken E. coli
May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ...
TMPH-00376 IL-8/CXCL8 Protein, Chicken, Recombinant Chicken E. coli
May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. ...
TMPY-04123 CEACAM1 Protein, Human, Recombinant (His & hFc) Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPJ-01187 Siglec-E Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Siglecs are sialic acid specific I‑type lectins that are characterized by an extracellular domain (ECD) with an N‑terminal Ig‑like V‑set domain followed by varying numbers of Ig‑like C2‑set domains. Mouse Siglec‑E, also ...
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc) Human HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPY-06707 Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-00828 Tau-F Protein, Human, Recombinant Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPJ-00808 CD45RA Protein, Human, Recombinant (His) Human HEK293 Cells
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPJ-01330 CD299 Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-S...
TMPH-01705 Mucin-1/MUC1 Protein, Human, Recombinant (His) Human E. coli
Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPY-00717 CEACAM1 Protein, Human, Recombinant (His) Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
TMPY-05717
Species: Human
Expression System: HEK293 Cells
VSIG8 Protein, Human, Recombinant (hFc)
TMPY-03225
Species: Human
Expression System: HEK293 Cells
VSIG8 Protein, Human, Recombinant (His)
TMPJ-00263
Species: Human
Expression System: HEK293 Cells
VSIG8 Protein, Mouse, Recombinant (His)
TMPJ-01180
Species: Mouse
Expression System: HEK293 Cells
IGSF3 Protein, Human, Recombinant (His)
TMPY-02243
Species: Human
Expression System: HEK293 Cells
Tenascin Protein, Human, Recombinant (E. coli, His)
TMPH-02187
Species: Human
Expression System: E. coli
IL-8/CXCL8 Protein, Chicken, Recombinant (His)
TMPH-00375
Species: Chicken
Expression System: E. coli
IL-8/CXCL8 Protein, Chicken, Recombinant
TMPH-00376
Species: Chicken
Expression System: E. coli
CEACAM1 Protein, Human, Recombinant (His & hFc)
TMPY-04123
Species: Human
Expression System: HEK293 Cells
Siglec-E Protein, Mouse, Recombinant (hFc)
TMPJ-01187
Species: Mouse
Expression System: HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
TMPY-00668
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)
TMPY-06707
Species: Human
Expression System: HEK293 Cells
Tau-F Protein, Human, Recombinant
TMPJ-00828
Species: Human
Expression System: E. coli
CD45RA Protein, Human, Recombinant (His)
TMPJ-00808
Species: Human
Expression System: HEK293 Cells
CD299 Protein, Human, Recombinant (His & Flag)
TMPJ-01330
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (His)
TMPH-01705
Species: Human
Expression System: E. coli
CEACAM1 Protein, Human, Recombinant (His)
TMPY-00717
Species: Human
Expression System: HEK293 Cells
TargetMol