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Search Results for " tpo "

Targets

17

Compounds

1

Natural Products

15

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T17146 TPO agonist 1 Others
TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.
T2562 Eltrombopag SB-497115,SB-497115-GR Thrombin
Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).
T6825 Eltrombopag Olamine Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR Thrombin
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom...
T7417 Avatrombopag YM477,AKR-501,E5501 Thrombin , Thrombopoietin Receptor
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
T3473 (S)-ATPO ATPO GluR
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
T17147 TPOP146 Epigenetic Reader Domain
TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).
TQ0223 Lusutrombopag S-888711,Mulpleta Thrombin , Thrombopoietin Receptor
Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
T67894 Butyzamide Thrombopoietin Receptor , JAK
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mou...
T68560 Totrombopag choline
Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and po...
T40654 Avatrombopag hydrochloride AKR-501 hydrochloride,YM477hydrochloride,E5501hydrochloride
Avatrombopag hydrochloride (AKR-501) is an orally active, nonpeptide agonist of the thrombopoietin (TPO) receptor with an EC 50 of 3.3 nM. It effectively mimics the biological activities of TPO, stimulating platelet prod...
T27536 Hetrombopag olamine
Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity.
T62865 Rafutrombopag
Rafutrombopag is a thrombopoietin (TPO) agonist.
T60281 MPO-IN-4
MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC 50 of 25 nM. MPO-IN-4 also demonstrates inhibition of thyroid peroxidase (TPO) with IC50 of 2.2 μM. MPO-IN-4 has no effect on me...
T68888 Avatrombopag maleate
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis througho...
T38602 (E/Z)-Eltrombopag 13C4 (E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead...
T72265 Eltrombopag methyl ester
Eltrombopag Methyl Ester, a derivative of Eltrombopag, functions as a thrombopoietin (Tpo) receptor agonist to enhance platelet production and is employed in the study of certain thrombocytopenia variants.
T40137 MPO-IN-1
MPO-IN-1 is a powerful and orally bioavailable indole-containing inhibitor that acts irrevocably on myeloperoxidase (MPO). With IC50 values of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively, MPO-IN-...
Cat No. Product Name Synonyms Targets
T3882 4”-O-Glucosylvitexin glucosylvitexin Thrombopoietin Receptor
4”-O-Glucosylvitexin (glucosylvitexin) inhibits TPO activity.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00939 Thrombopoietin Protein, Mouse, Recombinant (His) Mouse HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPJ-00235 TPO Protein, Human, Recombinant (His) Human Human Cells
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me...
TMPK-00940 C-MPL Protein, Mouse, Recombinant (aa 26-482, His) Mouse HEK293
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for m...
TMPY-04201 Thrombopoietin Protein, Human, Recombinant (hFc) Human HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPK-00494 C-MPL Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for m...
TMPK-00877 C-MPL Protein, Human, Recombinant (aa 26-491, His) Human HEK293
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for m...
TMPY-06863 C-MPL Protein, Mouse, Recombinant (His) Mouse HEK293
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPK-00874 Thyroid Peroxidase Protein, Mouse, Recombinant (His) Mouse HEK293
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon...
TMPJ-00071 EPO/Erythropoietin Protein, Human, Recombinant (His) Human Human Cells
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
TMPY-00639 EPO/Erythropoietin Protein, Human, Recombinant (hFc) Human HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00443 EPO/Erythropoietin Protein, Mouse, Recombinant Mouse HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-01609 Thrombopoietin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-02073 EPO/Erythropoietin Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00462 EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-02986 EPO/Erythropoietin Protein, Mouse, Recombinant (His) Mouse HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
Thrombopoietin Protein, Mouse, Recombinant (His)
TMPY-00939
Species: Mouse
Expression System: HEK293
TPO Protein, Human, Recombinant (His)
TMPJ-00235
Species: Human
Expression System: Human Cells
C-MPL Protein, Mouse, Recombinant (aa 26-482, His)
TMPK-00940
Species: Mouse
Expression System: HEK293
Thrombopoietin Protein, Human, Recombinant (hFc)
TMPY-04201
Species: Human
Expression System: HEK293
C-MPL Protein, Cynomolgus, Recombinant (His)
TMPK-00494
Species: Cynomolgus
Expression System: HEK293
C-MPL Protein, Human, Recombinant (aa 26-491, His)
TMPK-00877
Species: Human
Expression System: HEK293
C-MPL Protein, Mouse, Recombinant (His)
TMPY-06863
Species: Mouse
Expression System: HEK293
Thyroid Peroxidase Protein, Mouse, Recombinant (His)
TMPK-00874
Species: Mouse
Expression System: HEK293
EPO/Erythropoietin Protein, Human, Recombinant (His)
TMPJ-00071
Species: Human
Expression System: Human Cells
EPO/Erythropoietin Protein, Human, Recombinant (hFc)
TMPY-00639
Species: Human
Expression System: HEK293
EPO/Erythropoietin Protein, Mouse, Recombinant
TMPY-00443
Species: Mouse
Expression System: HEK293
Thrombopoietin Protein, Cynomolgus, Recombinant (His)
TMPY-01609
Species: Cynomolgus
Expression System: HEK293
EPO/Erythropoietin Protein, Rat, Recombinant (His)
TMPY-02073
Species: Rat
Expression System: Baculovirus-Insect Cells
EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His)
TMPY-00462
Species: Cynomolgus
Expression System: HEK293
EPO/Erythropoietin Protein, Mouse, Recombinant (His)
TMPY-02986
Species: Mouse
Expression System: HEK293
TargetMol