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Cat No. | Product Name | Synonyms | Targets |
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T17146 | TPO agonist 1 | Others | |
TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia. | |||
T2562 | Eltrombopag | SB-497115,SB-497115-GR | Thrombin |
Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110). | |||
T6825 | Eltrombopag Olamine | Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR | Thrombin |
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom... | |||
T7417 | Avatrombopag | YM477,AKR-501,E5501 | Thrombin , Thrombopoietin Receptor |
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production. | |||
T3473 | (S)-ATPO | ATPO | GluR |
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors. | |||
T17147 | TPOP146 | Epigenetic Reader Domain | |
TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4). | |||
TQ0223 | Lusutrombopag | S-888711,Mulpleta | Thrombin , Thrombopoietin Receptor |
Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. | |||
T67894 | Butyzamide | Thrombopoietin Receptor , JAK | |
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mou... | |||
T68560 | Totrombopag choline | ||
Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and po... | |||
T40654 | Avatrombopag hydrochloride | AKR-501 hydrochloride,YM477hydrochloride,E5501hydrochloride | |
Avatrombopag hydrochloride (AKR-501) is an orally active, nonpeptide agonist of the thrombopoietin (TPO) receptor with an EC 50 of 3.3 nM. It effectively mimics the biological activities of TPO, stimulating platelet prod... | |||
T27536 | Hetrombopag olamine | ||
Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity. | |||
T62865 | Rafutrombopag | ||
Rafutrombopag is a thrombopoietin (TPO) agonist. | |||
T60281 | MPO-IN-4 | ||
MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC 50 of 25 nM. MPO-IN-4 also demonstrates inhibition of thyroid peroxidase (TPO) with IC50 of 2.2 μM. MPO-IN-4 has no effect on me... | |||
T68888 | Avatrombopag maleate | ||
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis througho... | |||
T38602 | (E/Z)-Eltrombopag 13C4 | (E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4 | |
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead... | |||
T72265 | Eltrombopag methyl ester | ||
Eltrombopag Methyl Ester, a derivative of Eltrombopag, functions as a thrombopoietin (Tpo) receptor agonist to enhance platelet production and is employed in the study of certain thrombocytopenia variants. | |||
T40137 | MPO-IN-1 | ||
MPO-IN-1 is a powerful and orally bioavailable indole-containing inhibitor that acts irrevocably on myeloperoxidase (MPO). With IC50 values of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively, MPO-IN-... |
Cat No. | Product Name | Synonyms | Targets |
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T3882 | 4”-O-Glucosylvitexin | glucosylvitexin | Thrombopoietin Receptor |
4”-O-Glucosylvitexin (glucosylvitexin) inhibits TPO activity. |
Cat No. | Product Name | Species | Expression System |
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TMPY-00939 | Thrombopoietin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a... | |||
TMPJ-00235 | TPO Protein, Human, Recombinant (His) | Human | Human Cells |
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me... | |||
TMPK-00940 | C-MPL Protein, Mouse, Recombinant (aa 26-482, His) | Mouse | HEK293 |
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for m... | |||
TMPY-04201 | Thrombopoietin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a... | |||
TMPK-00494 | C-MPL Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for m... | |||
TMPK-00877 | C-MPL Protein, Human, Recombinant (aa 26-491, His) | Human | HEK293 |
The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for m... | |||
TMPY-06863 | C-MPL Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o... | |||
TMPK-00874 | Thyroid Peroxidase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon... | |||
TMPJ-00071 | EPO/Erythropoietin Protein, Human, Recombinant (His) | Human | Human Cells |
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi... | |||
TMPY-00639 | EPO/Erythropoietin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting... | |||
TMPY-00443 | EPO/Erythropoietin Protein, Mouse, Recombinant | Mouse | HEK293 |
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting... | |||
TMPY-01609 | Thrombopoietin Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a... | |||
TMPY-02073 | EPO/Erythropoietin Protein, Rat, Recombinant (His) | Rat | Baculovirus-Insect Cells |
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting... | |||
TMPY-00462 | EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting... | |||
TMPY-02986 | EPO/Erythropoietin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting... |