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Search Result

Search Results for " tpo "

Targets

Others

18

Compounds

1

Natural Products

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T17146 TPO agonist 1 Others
TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.
T2562 Eltrombopag SB-497115,SB-497115-GR Thrombin
Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).
T6825 Eltrombopag Olamine Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR Thrombin
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom...
T7417 Avatrombopag YM477,AKR-501,E5501 Thrombin , Thrombopoietin Receptor
Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
T3473 (S)-ATPO ATPO GluR
(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.
T17147 TPOP146 Epigenetic Reader Domain
TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).
TQ0223 Lusutrombopag S-888711,Mulpleta Thrombin , Thrombopoietin Receptor
Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
T67894 Butyzamide Thrombopoietin Receptor , JAK
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mou...
T68560 Totrombopag choline
Totrombopag, also known LGD-4665, GSK2285921 and SB559448, is an oral thromobopoietin receptor agonist, is being developed as a new generation small molecule thrombopoietin (TPO) mimetic. It is a highly selective and po...
T40654 Avatrombopag hydrochloride AKR-501 hydrochloride,YM477hydrochloride,E5501hydrochloride
Avatrombopag hydrochloride (AKR-501) is an orally active, nonpeptide agonist of the thrombopoietin (TPO) receptor with an EC 50 of 3.3 nM. It effectively mimics the biological activities of TPO, stimulating platelet prod...
T27536 Hetrombopag olamine
Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity.
T62865 Rafutrombopag
Rafutrombopag is a thrombopoietin (TPO) agonist.
T60281 MPO-IN-4
MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC 50 of 25 nM. MPO-IN-4 also demonstrates inhibition of thyroid peroxidase (TPO) with IC50 of 2.2 μM. MPO-IN-4 has no effect on me...
TMIH-0102 Avatrombopag-d8
Avatrombopag-d8 is a deuterated compound of Avatrombopag. Avatrombopag has a CAS number of 570406-98-3. Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocy...
T38602 (E/Z)-Eltrombopag 13C4 (E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead...
T68888 Avatrombopag maleate
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis througho...
T72265 Eltrombopag methyl ester
Eltrombopag Methyl Ester, a derivative of Eltrombopag, functions as a thrombopoietin (Tpo) receptor agonist to enhance platelet production and is employed in the study of certain thrombocytopenia variants.
T40137 MPO-IN-1
MPO-IN-1 is a powerful and orally bioavailable indole-containing inhibitor that acts irrevocably on myeloperoxidase (MPO). With IC50 values of 2.6 μM and 5.3 μM for MPO and thyroid peroxidase (TPO), respectively, MPO-IN-...
Cat No. Product Name Synonyms Targets
T3882 4”-O-Glucosylvitexin glucosylvitexin Thrombopoietin Receptor
4”-O-Glucosylvitexin (glucosylvitexin) inhibits TPO activity.

Natural Products

4”-O-Glucosylvitexin
T3882
Synonym: glucosylvitexin
Target: Thrombopoietin Receptor

Recombinant Proteins

Species：
Human (4)
Mouse (4)
Cynomolgus (1)
Expression System：
HEK293 Cells (9)
Tag：
C-His (5)
C-6xHis (1)
C-hFc (1)
His (1)
N, C-6xHis (1)
Cat No. Product Name Species Expression System
TMPY-00939 Thrombopoietin Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Thrombopoietin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is P40226-1.
TMPJ-00235 TPO Protein, Human, Recombinant (His) Human HEK293 Cells
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me...
TMPK-00940 C-MPL Protein, Mouse, Recombinant (aa 26-482, His) Mouse HEK293 Cells
C-MPL Protein, Mouse, Recombinant (aa 26-482, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.3 kDa and the accession number is Q08351-1.
TMPY-04201 Thrombopoietin Protein, Human, Recombinant (hFc) Human HEK293 Cells
Thrombopoietin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45 kDa and the accession number is P40225-1.
TMPK-00877 C-MPL Protein, Human, Recombinant (aa 26-491, His) Human HEK293 Cells
C-MPL Protein, Human, Recombinant (aa 26-491, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.6 kDa and the accession number is P40238-1.
TMPK-00494 C-MPL Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
C-MPL Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.48 kDa and the accession number is A0A2K5UGC7.
TMPY-06863 C-MPL Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
C-MPL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.64 kDa and the accession number is Q08351-1.
TMPK-00874 Thyroid Peroxidase Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon...
TMPJ-00071 EPO/Erythropoietin Protein, Human, Recombinant (His) Human HEK293 Cells
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
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