tcr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T78271	Anti-Mouse TCR gamma/delta Antibody (UC7-13D5)
	Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.
T83034	Anti-Mouse TCR V gamma 2 Antibody (UC3-10A6)
	Anti-Mouse TCR V gamma 2 Antibody is a host Armenian Hamster-derived IgG inhibitory antibody targeting mouse TCR V gamma 2.
T14193	α-Galactosylceramide	KRN7000,α-GalCer	Others
	α-Galactosylceramide (KRN7000) is a synthetic glycolipid with antitumorial and immunostimulatory and is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide and CD1d can bind ...		Others
T81027	TCRS-417	T417
	TCRS-417 (T417), a small molecule compound, selectively binds to the interface between PBX1 and its specific DNA target sequence, disrupting the PBX1-DNA interaction. This compound has potential research applications in ...
T35885	KRM-III		Others
	KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell ...		Others
TP1541L	BDC2.5 mimotope 1040-31 acetate	BDC2.5 mimotope 1040-31 acetate(329696-49-3 free base)	Others
	BDC2.5 mimotope 1040-31 acetate is a effectively agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5. It can stimulate BDC2.5 cells with cells showing good response to this mimotope. 1040-31 peptide is spec...		Others
T4403	AX-024 hydrochloride	AX-024 HCl	IL Receptor , TNF , COX , IFNAR , Interleukin
	AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.		IL Receptor , TNF , COX , IFNAR , Interleukin
T78369	QL9 TFA
	QL9 (QLSPFPFDL) TFA is an alloantigen that exhibits high affinity for the 2C T cell receptor (TCR).
T82908	BDC2.5 mimotope 1040-31 TFA
	BDC2.5 mimotope 1040-31 TFA, a specific agonistic peptide for the diabetogenic T cell clone BDC2.5, exhibits strong reactivity with BDC2.5 T-cell receptor (TCR) transgenic (Tg)+ T cells [1] [2].
T61071	AX-024
	AX-024 is a novel chemical compound that acts as an orally available inhibitor of the TCR-Nck interaction. Its primary mechanism of action is the selective inhibition of T cell activation triggered by TCR stimulation. Wi...
T80744	Zanolimumab	Anti-Human CD4 Recombinant Antibody
	Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody that targets the CD4 molecule and effectively inhibits T-cell receptor (TCR) signal transduction. It is used in the research of rheum...
TP1541	BDC2.5 mimotope 1040-31
	This is a effectively agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5. It can stimulate BDC2.5 cells with cells showing good response to this mimotope. 1040-31 peptide is specific for BDC2.5 TCR Tg+ (tr...
TP1855	Moth Cytochrome C (MCC) (88-103)	Moth Cytochrome C (MCC) 88-103
	Moth Cytochrome C (MCC) (88-103), derived from the carboxyl terminus of moth cytochrome c, induces positive selection of TCR transgenic thymocytes.This peptide is derived from the carboxyl terminus of moth cytochrome c. ...
T76254	CD31
	CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a receptor on endothelial cells for clostridium perfringens beta-Toxin (CPB). It also functions as an ER-MP12 antigen and connects mechanica...
T37604	ITK inhibitor
	Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine recept...
T79635	LYP-IN-4		Phosphatase
	LYP-IN-4 (compound D14), a reversible and selective lymphotyrosine phosphatase (LYP) inhibitor (Ki=1.34 μM, IC50=3.52μM), regulates TCR signaling, increases PD-1/PD-L1 expression, and strengthens anti-tumor immunity. It ...		Phosphatase
T76254L	CD31 TFA
	CD31 TFA, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), functions as the specific receptor for Clostridium perfringens beta-Toxin (CPB) in endothelial cells. It is recognized as an ER-MP12 antige...
T79634	LYP-IN-3		Phosphatase
	LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway during tumor progression. It promotes T-cell activation, hinder...		Phosphatase
T76843	Tebentafusp
	Tebentafusp (IMCgp100) is a bispecific fusion protein designed to target the gp100 peptide-HLA-A*02:01 complex, a melanoma-associated antigen. It directs T cells towards melanoma cells expressing gp100 through a high-aff...
T82907	BDC2.5 Mimotope 1040-63
	BDC2.5 Mimotope 1040-63 is a biologically active peptide employed in the investigation of type 1 diabetes (T1D), an autoimmune disease where T cells induce destruction of pancreatic islet β cells. This mimotope, originat...