tapi — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6009	TAPI1	TAPI 1,TAPI,TAPI-1	MMP
	TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.		MMP
TP2107	TAPI 0
	ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
TP2108	TAPI 2
	ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.
TQ0129	TNF Protease Inhibitor 2	TAPI-2	MMP
	TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).		MMP
T4122	TAPI-1 trifluoroacetate (163847-77-6(free base))		MMP
	TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.		MMP
T70664	TAPI-0
	TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.
T63390	(S,S)-TAPI-1
	(S,S)-TAPI-1 is an isomer of TAPI-1. Among them, TAPI-1 is a metalloproteinase (MMP) inhibitor and a TACE (ADAM17) inhibitor that exhibits potent inhibition of a variety of cell surface protein shedding.
T2545	Lomitapide Mesylate	BMS-201038 mesylate,AEGR-733 mesylate	CETP
	Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.		CETP
T7459	Abametapir	HA-44,BRN 0123183	MMP , Others , Parasite
	Abametapir (BRN 0123183), a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.		MMP , Others , Parasite
T15006	Dirlotapide	CP742033,Slentrol	Others , CETP
	Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by ...		Others , CETP
T4644	Tapinarof	GSK2894512,Benvitimod,WBI 1001	AhR , Aryl Hydrocarbon Receptor
	Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.		AhR , Aryl Hydrocarbon Receptor
T6267	Lomitapide	AEGR-733,BMS-201038	CETP
	Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring...		CETP
T3179	Eptapirone	F 11440	5-HT Receptor
	Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential.		5-HT Receptor
T35316	Zometapine	CI 716,Zolazepamum,CI-716,CI716,Flupyrazapon	Others
	Zometapine (CI 716) is an antidepressant compound that is a derivative of pyrazole and diazepine.		Others
T31992	Granotapide		CETP
	Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an...		CETP
T4223	Mitapivat	PKR-IN-1	PKM
	Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.		PKM
T70183	Eptapirone fumarate
	Eptapirone, also known as F11440, is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (...
T41082	Flobetapir	AV-45,Flobetapir
	Flobetapir (AV-45) is a well-tolerated imaging compound used in PET scanning. It is synthesized to create Florbetapir (18F), which is a radiopharmaceutical compound containing fluorine-18 radionuclide.
T69677	Mitapivat sulfate anhydrous
	Mitapivat sulfate anhydrous is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency.
T10504	Implitapide Racemate		Others
	Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).		Others