statins — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0683	Mevastatin	Compactin,ML236B	Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
	Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T67906	Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate)
	Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate) is a compound that is a phosphoric acid derivative of compound statins.
T3625	Bempedoic acid	ETC1002,ESP-55016,ETC 1002,ETC-1002	ATP Citrate Lyase , AMPK
	Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic ...		ATP Citrate Lyase , AMPK
T1676	Rosuvastatin	ZD 4522	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...		Potassium Channel , HMG-CoA Reductase , Autophagy
T71628	Fluvastatin potassium
	Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is ...
T71560	Atorvastatin magnesium trihydrate
	Atorvastatin magnesium trihydrate is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase...
T71492	Atorvastatin strontium
	Atorvastatin strontium is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme...
T11572	HMG499		HMG-CoA Reductase
	HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC 50 of 0.41 μM. HMG499 can eliminate statins-induced accumulation of HMGCR, lower serum cholesterol levels and decrease atherosclerosis [1].		HMG-CoA Reductase
T76800	Dalotuzumab
	Dalotuzumab (MK-0646) is a humanized recombinant monoclonal antibody (IgG1 type) that targets IGF-1R, inhibiting tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation mediated by IGF-1 and IGF-2. ...
T82900	Bemfivastatin hemicalcium	PPD 10558 hemicalcium
	Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent. It amplifies liver extract activity and exhibits no-observed adverse effect levels (NOAEL) at dosages...