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Search Results for " sb2 "

14

Compounds

Cat No. Product Name Synonyms Targets
T23861 CAY10526 CAY-10526,BTH,CAY 10526 Prostaglandin Receptor
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
T1955 SB225002 CXCR
SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.
T12851 SB290157 trifluoroacetate Complement System
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).
T4674 SB297006 SB 297006 CCR
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...
T16856 SB228357 5-HT Receptor
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
T6657 SB273005 Integrin
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
T75013 SB26019
SB26019 is a potent anti-neuroinflammatory compound that modulates the activation of NF-κB by promoting the formation of monomeric α-tubulin. This action of SB26019, in turn, hinders the translocation of p65, signifying ...
T16857 SB269652 Others
SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor.
T28681 SB220025 SB-220025,SB 220025
SB220025, a specific and potent inhibitor of human p38 mitogen-activated protein kinase, reduces the production of tumor necrosis factor induced by lipopolysaccharide.
T28688 SB2602 SB-2602,SB 2602
SB2602 selectively inhibits mTOR.
T82961 ASB20123
ASB20123, a CNP/ghrelin chimeric peptide, promotes bone growth and has potential research applications in growth disorders and dwarfism [1].
T28683 SB234551 SB 234551,SB-234551
SB234551 is a selective antagonist of endothelin ETA receptor.
T28685 SB236057 SB-236057,SB 236057
SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a pote...
T28687 SB251023 SB-251023,SB 251023
SB251023 is an agonist of β3-adrenoceptor.
TargetMol