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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23861 | CAY10526 | CAY-10526,BTH,CAY 10526 | Prostaglandin Receptor |
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway. | |||
T1955 | SB225002 | CXCR | |
SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2. | |||
T12851 | SB290157 trifluoroacetate | Complement System | |
SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM). | |||
T4674 | SB297006 | SB 297006 | CCR |
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ... | |||
T16856 | SB228357 | 5-HT Receptor | |
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively. | |||
T6657 | SB273005 | Integrin | |
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively. | |||
T75013 | SB26019 | ||
SB26019 is a potent anti-neuroinflammatory compound that modulates the activation of NF-κB by promoting the formation of monomeric α-tubulin. This action of SB26019, in turn, hinders the translocation of p65, signifying ... | |||
T16857 | SB269652 | Others | |
SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor. | |||
T28681 | SB220025 | SB-220025,SB 220025 | |
SB220025, a specific and potent inhibitor of human p38 mitogen-activated protein kinase, reduces the production of tumor necrosis factor induced by lipopolysaccharide. | |||
T28688 | SB2602 | SB-2602,SB 2602 | |
SB2602 selectively inhibits mTOR. | |||
T82961 | ASB20123 | ||
ASB20123, a CNP/ghrelin chimeric peptide, promotes bone growth and has potential research applications in growth disorders and dwarfism [1]. | |||
T28683 | SB234551 | SB 234551,SB-234551 | |
SB234551 is a selective antagonist of endothelin ETA receptor. | |||
T28685 | SB236057 | SB-236057,SB 236057 | |
SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a pote... | |||
T28687 | SB251023 | SB-251023,SB 251023 | |
SB251023 is an agonist of β3-adrenoceptor. |