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Search Results for " raloxifene "

20

Compounds

Cat No. Product Name Synonyms Targets
T20419 Raloxifene Pharoxifene,Raloxifenum,Keoxifene,LY-139481 Estrogen Receptor/ERR , Others
Raloxifene (LY-139481) is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.
T1549 Raloxifene hydrochloride LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl Estrogen Receptor/ERR , Others , MAO , Estrogen/progestogen Receptor , Autophagy
Raloxifene hydrochloride (LY156758 hydrochloride) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and chol...
T40938 Raloxifene dimethyl ester hydrochloride Diacyl-raloxifene hydrochloride,Raloxifenediacylanalog
Raloxifene dimethyl ester hydrochloride is an analog of Raloxifene.
T39298 Raloxifene 4-Monomethyl Ether
Raloxifene 4-Monomethyl Ether (Compound 37) is a derivative of Raloxifene which acts as an inhibitor of estrogen receptor α. It effectively suppresses the activity of MCF-7 cells, exhibiting an IC50 value of 1 μM and a p...
T39203 Raloxifene 6-Monomethyl Ether
Compound 7, or Raloxifene 6-Monomethyl Ether, is a derivative of Raloxifene that effectively inhibits estrogen receptor α. It also displays the inhibitory effects on MCF-7 cells, with an IC50 of 250 nM and a pIC50 of 6.6...
T19545 Raloxifene N-Oxide Others
Raloxifene N-Oxide is a Raloxifene oxidative degradation product.
T12686 Raloxifene 4'-glucuronide Others
Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene.
T12688 Raloxifene 6-glucuronide Others
Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8.
T19544 Raloxifene Bismethyl Ether Others
Raloxifene Bismethyl Ether is a Raloxifene metabolite and an estrogen receptor inactive compound on which both hydroxyl groups are absent.
T19543 Raloxifene Bismethyl Ether hydrochloride Others
Raloxifene Bismethyl Ether hydrochloride is a Raloxifene metabolite and an estrogen receptor inactive compound on which both hydroxyl groups are absent.
T10187 6-Raloxifene-β-D-glucopyranoside Others
6-Raloxifene-β-D-glucopyranoside is a benzothiophene glucuronidated at the 6' position. It is a selective and orally active estrogen receptor antagonist. 6-Raloxifene-β-D-glucopyranoside can be used for inhibiting bone l...
T10155 4'-Raloxifene-β-D-glucopyranoside Others
4'-Raloxifene-β-D-glucopyranoside is a metabolite of Raloxifene. 4'-Raloxifene-β-D-glucopyranoside is a selective and orally active estrogen receptor antagonist.
T12687 Raloxifene 6,4'-Bis-β-D-glucuronide Others
Raloxifene 6,4'-Bis-β-D-glucuronide is a Raloxifene metabolite. Raloxifene is a selective antagonist of estrogen receptor for the prevention of osteoporosis.
T19141 4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene Others
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene is a reaction product of Raloxifene with tertbutyldimethylsilyl chloride.
T10189 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene Others
7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is a liver receptor homolog-1 (LRH-1) antagonist (IC50: 3.1 μM).
T19425 Methyl Raloxifene 4'-(2,3,4-Tri-O-acetyl-β-D-glycopyranuronate) Others
Methyl Raloxifene 4'-(2,3,4-Tri-O-acetyl-β-D-glycopyranuronate) is a derivative compound of Raloxifene 4'-glucuronide, designed to resemble its structure and function.
T9001 Desketoraloxifene Phospholipase
Desketoraloxifene is a selective estrogen receptor modulator, inhibiting mammalian PLD (PLD1 and PLD2).
T11915 LY88074 Estrogen/progestogen Receptor
LY88074 is a raloxifene analog in which the basic side chain has been removed. LY88074 is an agonist of ERβ (EC50 = 232 nM).This compound stimulates uterine cell proliferation.
TN2211 Silybin B Silibinin B Apoptosis , Beta Amyloid , Bcr-Abl
Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with free radical scavenging activity of 1, 1-dipheny...
T15800 LY117018 PI3K
LY117018 shows antiproliferative effects on breast cancer cell lines. LY117018 is a Raloxifene analog and is a selective estrogen receptor modulator.

Compounds

Raloxifene
T20419
Synonym: Pharoxifene,Raloxifenum,Keoxifene,LY-139481
Target: Estrogen Receptor/ERR, Others
Raloxifene hydrochloride
T1549
Synonym: LY156758 hydrochloride,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl
Target: Estrogen Receptor/ERR, Others, MAO, Estrogen/progestogen Receptor, Autophagy
Raloxifene dimethyl ester hydrochloride
T40938
Synonym: Diacyl-raloxifene hydrochloride,Raloxifenediacylanalog
Target:
Raloxifene 4-Monomethyl Ether
T39298
Synonym:
Target:
Raloxifene 6-Monomethyl Ether
T39203
Synonym:
Target:
Raloxifene N-Oxide
T19545
Synonym:
Target: Others
Raloxifene 4'-glucuronide
T12686
Synonym:
Target: Others
Raloxifene 6-glucuronide
T12688
Synonym:
Target: Others
Raloxifene Bismethyl Ether
T19544
Synonym:
Target: Others
Raloxifene Bismethyl Ether hydrochloride
T19543
Synonym:
Target: Others
6-Raloxifene-β-D-glucopyranoside
T10187
Synonym:
Target: Others
4'-Raloxifene-β-D-glucopyranoside
T10155
Synonym:
Target: Others
Raloxifene 6,4'-Bis-β-D-glucuronide
T12687
Synonym:
Target: Others
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene
T19141
Synonym:
Target: Others
7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene
T10189
Synonym:
Target: Others
Methyl Raloxifene 4'-(2,3,4-Tri-O-acetyl-β-D-glycopyranuronate)
T19425
Synonym:
Target: Others
Desketoraloxifene
T9001
Synonym:
Target: Phospholipase
LY88074
T11915
Synonym:
Target: Estrogen/progestogen Receptor
Silybin B
TN2211
Synonym: Silibinin B
Target: Apoptosis, Beta Amyloid, Bcr-Abl
LY117018
T15800
Synonym:
Target: PI3K
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TargetMol