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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T61766 | RSK4-IN-1 | ||
RSK4-IN-1 is a compound exhibiting potent inhibition of RSK4, demonstrated by an IC50 value of 9.5 nM. | |||
T6171 | BI-D1870 | S6 Kinase , Autophagy | |
BI-D1870 is a cell-permeable, ATP-competitive inhibitor of ribosomal S6 kinases (RSKs; IC50s: 31/24/18/15 nM for RSK1/2/3/4). | |||
T6948 | Pluripotin | SC1 | ERK , Raf , S6 Kinase |
Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. | |||
T73350 | BAY-3827 | Acyltransferase , AMPK | |
BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, showing antiproliferative activity in an androgen-dependent prostate cancer model. BAY-3827 inhibits the phosphorylation of acetyl CoA ... | |||
T21295 | BIX02189 | BIX 02189 | ERK , MEK |
BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM). | |||
T1744 | BIX02188 | Apoptosis , MEK | |
BIX02188 is a selective and potent MEK5 inhibitor that inhibits MEK5-induced apoptosis in cells expressing the oncogenic mutant FLT3-ITD. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04357 | RSK4 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 9 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kina... | |||
TMPH-01692 | MAPK3 Protein, Human, Recombinant (His) | Human | E. coli |
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate... |