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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8931L | ICCB-19 hydrochloride | ICCB-19 HCl(750621-52-4 free base) | Apoptosis , Others , Autophagy , RIP kinase |
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal dom... | |||
T17284 | Zardaverine | BY 290,B 84290 | PDE |
Zardaverine (BY 290) is an orally available, selective and potent PDE3/4 inhibitor with bronchodilator activity and anti-hepatocarcinogenic activity.Zardaverine's action in platelets is mediated by PDE III isoenzymes and... | |||
TN3594 | Cardanol (C15:1) | Apoptosis , Others | |
Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells. | |||
T2994 | (E)-Cardamonin | Alpinetin chalcone,Cardamomin,Cardamonin,(E)-Cardamoni | Apoptosis , TRP/TRPV Channel |
(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM... | |||
T20642 | Laurdan | 6-Dodecanoyl-2-dimethylaminonaphthalene | Others |
Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene) is a fluorescent membrane probe that is spectrally sensitive to the phospholipid phase of the cell membrane to which it binds. | |||
T32191 | Irdabisant | CEP-26401,CEP 26401,CEP26401 | Histamine Receptor |
Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant ex... | |||
TJS0328 | Nordalbergin | 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One | Others |
Nordalbergin, a coumarin isolated from the bark of Dalbergia sissoo, can significantly induce the differentiation of HL-60 cells. | |||
T6189 | Mirdametinib | PD325901,PD0325901 | Apoptosis , MEK , Autophagy |
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis. | |||
T3726 | Erdafitinib | JNJ-42756493 | Apoptosis , FGFR |
Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4. | |||
T33483 | Mordant red 19 | NSC-326195,NSC 326195,Acid Chrome Red 5G,Superchrome Red G,NSC326195 | |
Mordant red 19 is an azo dye. | |||
T36539 | Nocardamine | ||
Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. b... | |||
T36434 | Sordarin sodium | ||
Sordarin is an inhibitor of fungal protein synthesis originally isolated from S. araneosa.[1] It binds to elongation factor 2 (EF-2) in the presence of ribosomes and inhibits the uncoupled GTPase activity of equimolar mi... | |||
T71813 | Cardanol diene | ||
Cardanol diene is a phenol found in cashew nut shell liquid that inhibits tyrosinase with an IC50 value of 52.5 μM in vitro. Cardanol diene is also used to synthesize cardanol-metal complexes that inhibit uropathogenic E... | |||
T125463 | 12-O-Methylsordariol | ||
12-O-Methylsordariol is a useful organic compound for research related to life sciences. The catalog number is T125463 and the CAS number is 1938054-84-2. | |||
T126401 | Cordatin | ||
Cordatin is a useful organic compound for research related to life sciences. The catalog number is T126401 and the CAS number is 110382-43-9. | |||
T10795 | Chlordantoin | Clodantoin | Others |
Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment. | |||
T36477 | Urdamycin A | ||
Urdamycin A is a bacterial metabolite originally isolated fromS. fradiaethat has antibacterial and anticancer activities.1,2It is active against a variety of Gram-positive and Gram-negative bacteria, includingB. subtilis... | |||
T37555 | Cardanol triene | ||
Cardanol triene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 40.5 μM in vitro. A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal c... | |||
T61197 | Irdabisant hydrochloride | ||
Irdabisant hydrochloride (CEP-26401) is a selective, orally active, and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist, demonstrating high affinity with K*i values of 7.2 ... | |||
T126318 | Sordariol | ||
Sordariol is a useful organic compound for research related to life sciences. The catalog number is T126318 and the CAS number is 115873-03-5. |