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Search Results for " rantes "

11

Compounds

1

Natural Products

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T76567 Met-RANTES (human)
Met-RANTES (human), a partial antagonist of CCR5, diminishes the infiltration of blood monocytes into the liver [1].
T21938 AS-041164 PI3K
AS-041164 is a selective and orally active PI3Kγ isoform inhibitor(IC50 of 70 nM), and shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). It has anti-inflammatory e...
T6016 Maraviroc Celsentri,UK-427857,Selzentry HIV Protease , CCR
Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.
T4674 SB297006 SB 297006 CCR
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...
T24735 RP-23618
RP-23618 is a non-peptidic antagonist of RANTES.
T16973 TAK-220 HIV Protease
TAK-220 is a selective and orally bioavailable CCR5 antagonist (IC50s: 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respectively).
T35453 β-Defensin-4 (human) (trifluoroacetate salt)
β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T35452 β-Defensin-3 (human) (trifluoroacetate salt)
β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T35451 β-Defensin-2 (human) (trifluoroacetate salt)
β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...
T7499 TAK-779 Takeda 779 HIV Protease , CXCR , CCR
TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
T14845 BX471 hydrochloride ZK-811752 hydrochloride Others
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.
Cat No. Product Name Synonyms Targets
TN1347 8-Prenylkaempferol p38 MAPK , NF-κB , PI3K
8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated tran...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00009 CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited n...
TMPK-00008 CCL5 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited n...
TMPY-01072 CCL5 Protein, Human, Recombinant (His & mucin) Human HEK293 Cells
CCL5 Protein, Human, Recombinant (His & mucin) is expressed in HEK293 mammalian cells with His and mucin tag. The predicted molecular weight is 34 kDa and the accession number is D0EI67.
TMPY-04214 CCL5 Protein, Human, Recombinant Human E. coli
CCL5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is D0EI67.
TMPJ-00993 CCL5 Protein, Rat, Recombinant (E. coli, His) Rat E. coli
C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory s...
TMPJ-00018 CCL16 Protein, Human, Recombinant Human E. coli
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC c...
TargetMol