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Search Results for " prp "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T23450	TCS PrP Inhibitor 13	5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One	Others
	TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.		Others
T34172	PRP-194
	PRP-194, CAS#596085-87-9, has a chemical name 5-chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine, is a useful precursor for chemical synthesis of bioactive molecules and dyes. There is no formal name for this chemical. F...
TP1850	PACAP-Related Peptide (PRP), human
	PACAP-Related Peptide (PRP), human,a 29 amino-acid region of the PACAP precursor protein, is synthesized in quantities sufficient for biological and structural studies.
TP1060	GPRP acetate (67869-62-9 free base)	Pefabloc FG,Pefa 6003,GPRP acetate	Others
	GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex (GPIIbIIIa).		Others
T39269	CPrPMEDAP
	cPrPMEDAP, an intermediate metabolite of GS-9219, acts as a prodrug for the guanine nucleotide analog PMEG, demonstrating antiproliferative activity. It is negatively charged at physiological pH, resulting in poor skin p...
T27419	GPRP	Gly-Pro-Arg-Pro Acetate,Gly-Pro-Arg-Pro Acetate salt
	Gly-Pro-Arg-Pro Acetate, an inhibitor of fibrinogen aggregation, acts by binding to fibrinopeptide A.
T12563	PrPSc-IN-1		Others
	PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation(IC50 of 1.6 μM), with anti-prion activity.		Others
T40363	Poly-D-lysine hydrobromide (MW 30000-70000)	Poly-D-lysine HBr (MW 30000-70000)	CaSR
	Poly-D-lysine hydrobromide (MW 30000-70000)(Poly-D-lysine HBr) is an orally available peptide CaSR agonist that removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.		CaSR
T8556	Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)	Z-Gly-Gly-Arg-AMC TFA	Others
	Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base) is a thrombin-specific fluorogenic substrate for testing thrombin generation in PRP and platelet-poor plasma (PPP).		Others
T2194	Direct Blue 1	Pontamine sky blue,Chicago Sky Blue 6B	GluR
	Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacti...		GluR
T12215	Nexopamil racemate	(Rac)-Nexopamil	Calcium Channel , 5-HT Receptor
	Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.		Calcium Channel , 5-HT Receptor
T27314	Fe-TMPyP
	Fe-TMPyP binds to the prion protein PrP and inhibits misfolding. Fe-TMPyP is also a peroxynitrite decomposition catalyst.
T60775	BB 0305179
	BB 0305179 (compound 59) inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain. BB 0305179 is a potent anti-prion agent (IC 50 = 4.7 μM) [1].
T27605	IND45193	IND-45193,IND 45193
	IND45193, an antiprion agent, acts by reducing PrP(Sc) levels in dividing and stationary-phase cells.
TP1799	Z-Gly-Gly-Arg-AMC
	Z-Gly-Gly-Arg-AMC is a specific fluorogenic substrate utilized for assessing thrombin generation in Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP), with a particular focus on thrombin activity.
T27408	Gea 3162	Gea3162,Gea-3162
	Gea 3162 is a potent inhibitor of ADP-induced platelet aggregation in platelet rich plasma (PRP). GEA 3162 stimulates cGMP production in granulocytes, platelets, and polymorphonuclear leukocytes.
T81312	Ralzapastotug	AB-308
	Ralzapastotug (AB-308) is a monoclonal antibody that targets amino acids 106-126 of the prion protein PrP^C[1].
T71851	5-trans-Prostaglandin E2
	5-trans-Prostaglandin E2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP.
T36428	PACAP-related Peptide (human) (trifluoroacetate salt)		PACAP
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adeny...		PACAP
T83807	Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium	Rp-ATP-α-S
	Rp-Adenosine-5'-O-(1-thiotriphosphate) (Rp-ATP-α-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 recept...
TP1298	Z-Gly-Gly-Arg-AMC acetate
	Z-Gly-Gly-Arg-AMC acetate is a thrombase-specific fluorescent matrix for the detection of thrombin production in PRP and poor platelet plasma (PPP).
T37435	PACAP-related Peptide (rat) (trifluoroacetate salt)		PACAP
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adeny...		PACAP
T73416	BiCAPPA
	BiCAPPA, a pioneering bivalent antiprion ligand, effectively reduces the infectious conformational form of prion protein (PrP Sc) in scrapie-infected cells, achieving this at a concentration (EC 50) of 0.32 μM.
T36774	13,14-dehydro-15-cyclohexyl Carbaprostacyclin
	13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is c...
T36775	13,14-dihydro Prostaglandin E1	13,14-dihydro Prostaglandin E1
	13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and wash...
T12316	Oral antiplatelet agent 1		Others
	Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro.		Others

Compounds

TCS PrP Inhibitor 13

T23450

Synonym: 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One

PACAP-Related Peptide (PRP), human

TP1850

Synonym:

Target:

GPRP acetate (67869-62-9 free base)

TP1060

Synonym: Pefabloc FG,Pefa 6003,GPRP acetate

Synonym: Gly-Pro-Arg-Pro Acetate,Gly-Pro-Arg-Pro Acetate salt

Poly-D-lysine hydrobromide (MW 30000-70000)

T40363

Synonym: Poly-D-lysine HBr (MW 30000-70000)

Target: CaSR

Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)

T8556

Synonym: Z-Gly-Gly-Arg-AMC TFA

Target: Others

Direct Blue 1

T2194

Synonym: Pontamine sky blue,Chicago Sky Blue 6B

Target: GluR

Nexopamil racemate

T12215

Synonym: (Rac)-Nexopamil

Target: Calcium Channel, 5-HT Receptor

Synonym: IND-45193,IND 45193

Synonym: Gea3162,Gea-3162

5-trans-Prostaglandin E2

Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium

T83807

Synonym: Rp-ATP-α-S

Target:

Z-Gly-Gly-Arg-AMC acetate

13,14-dehydro-15-cyclohexyl Carbaprostacyclin

T36774

Synonym:

Target:

13,14-dihydro Prostaglandin E1

T36775

Synonym: 13,14-dihydro Prostaglandin E1

Target:

Oral antiplatelet agent 1

T12316

Synonym:

Target: Others

Cat No.	Product Name	Synonyms	Targets
TN1270	LPRP-Et-97543	(3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one	Others
	(3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one is a natural product		Others

Natural Products

LPRP-Et-97543

TN1270

Synonym: (3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00775	PRNP/Prion Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Prion protein gene (PRNP) variants determine the susceptibility of humans, sheep and mice to prion diseases, whereas polymorphisms in the open reading frame (ORF) of bovine PRNP seem to be unrelated to the incidence of b...
TMPY-02200	Peroxiredoxin 2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm pro...
TMPY-05169	Peroxiredoxin 2 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm pro...
TMPY-03842	PRNP/Prion Protein Protein, Human, Recombinant (hFc)	Human	HEK293
	Prion protein (PRNP) gene is well known for affecting mammal transmissible spongiform encephalopathies (TSE), and is also reported to regulate phenotypic traits (e.g. growth traits) in healthy ruminants. PRNP is fundamen...
TMPH-00492	PNLIPRP1 Protein, Canine, Recombinant (His & SUMO)	Canine	E. coli
	PNLIPRP1 Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-04768	PRPS2 Protein, Human, Recombinant (His)	Human	E. coli
	PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via th...
TMPY-03808	PNLIPRP1 Protein, Human, Recombinant (His)	Human	HEK293
	PNLIPRP1, also known as PLRP1, belongs to the AB hydrolase superfamily, Lipase family. PNLIPRP1 is structurally similar to PLRP2. However, these two proteins display different functional properties. PNLIPRP1 may function...
TMPY-00252	PNLIPRP1 Protein, Rat, Recombinant (His)	Rat	HEK293
	PNLIPRP1, also known as PLRP1, belongs to the AB hydrolase superfamily, Lipase family. PNLIPRP1 is structurally similar to PLRP2. However, these two proteins display different functional properties. PNLIPRP1 may function...
TMPH-00491	PNLIPRP1 Protein, Canine, Recombinant (His)	Canine	Yeast
	PNLIPRP1 Protein, Canine, Recombinant (His) is expressed in Yeast.