Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 36.00 | |
2 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 289.00 | |
50 mg | In stock | $ 455.00 | |
100 mg | In stock | $ 672.00 | |
500 mg | In stock | $ 1,430.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 113.00 |
Description | TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation. |
Targets&IC50 | PrPC:3 nM (in ScN2a and F3 cells) |
In vitro | In Schwannoma cells, administration of 0-500 μM TCS PrP Inhibitor 13 reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and increases expression of cleaved caspase-3 significantly. TCS PrP Inhibitor 13 also significantly reduces the number of proliferating, Ki67-positive cells and total cell number in Schwannoma cells[2]. |
Synonyms | 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One |
Molecular Weight | 281.27 |
Formula | C15H11N3O3 |
CAS No. | 34320-83-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 88 mg/mL (312.87 mM)
You can also refer to dose conversion for different animals. More
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TCS PrP Inhibitor 13 34320-83-7 Others Inhibitor inhibit cellular 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One ScN2a agent Apoptosis antiprion protease-resistant TCS PrP Inhibitor13 prion TCS PrP Inhibitor-13 inhibitor