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Cat No. | Product Name | Synonyms | Targets |
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T78324 | Ociperlimab | BGB-A1217 | |
Ociperlimab, a humanized IgG1 anti-TIGIT antibody, exhibits high affinity for the extracellular domain of human TIGIT, with a dissociation constant (K_D) of 0.135 nM. It effectively inhibits the interaction between TIGIT... | |||
T28877 | SU9518 | SU 9518,5-Br-SU6668,SU-9518,5 Br SU6668,5BrSU6668 | |
SU9518, a tyrosine kinase inhibitor with PDGFRα specificity, can inhibit the development of proliferative vitreoretinopathy (PVR) in fibroblast and Müller cell rabbit models. | |||
T82436 | Etigilimab | OMP-313M32 | |
Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, inhibits TIGIT from interacting with PVR (CD155; poliovirus receptor) and suppresses subsequent signaling, resulting in target cell death [1]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00651 | CD155/PVR Protein, Human, Recombinant (aa 21-343, His) | Human | HEK293 Cells |
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entr... | |||
TMPY-05791 | CD155/PVR Protein, Mouse, Recombinant (mFc) | Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094. | |||
TMPY-00699 | CD155/PVR Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1. | |||
TMPY-01386 | CD155/PVR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P15151-1. | |||
TMPY-01612 | CD155/PVR Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q0MSE6. | |||
TMPK-00260 | CD155/PVR Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells... | |||
TMPY-00762 | CD155/PVR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is Q8K094. | |||
TMPY-01610 | CD155/PVR Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CD155/PVR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is A6J8V8. | |||
TMPY-05597 | CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated | Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 62.9 kDa and the accession number is Q8K094. | |||
TMPY-05596 | CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.3 kDa and the accession number is P15151.2. | |||
TMPY-06133 | CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 63.6 kDa and the accession number is P15151-1. | |||
TMPY-01150 | Nectin-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Nectin-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P32507-1. | |||
TMPY-06094 | PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 Cells |
PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is XP_005549281.1&XP_014989941.2. | |||
TMPY-05579 | PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPK-00470 | PVRIG Protein, Mouse, Recombinant (hFc & Avi) | Mouse | HEK293 Cells |
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVR... | |||
TMPK-00471 | PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated | Mouse | HEK293 Cells |
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVR... | |||
TMPY-05196 | PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.9 kDa and the accession number is Q9JKF6. | |||
TMPJ-00436 | PVRIG Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
PVRIG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is A0A2K5WVV8. | |||
TMPY-02937 | PVRL1/NECTIN1 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
PVRL1/NECTIN1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is A6J3U6. | |||
TMPY-01572 | PVRL1/NECTIN1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.4 kDa and the accession number is Q15223-1. | |||
TMPJ-00435 | PVRIG Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
PVRIG Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-55 KDa and the accession number is A0A2K5WVV8. | |||
TMPJ-00428 | PVRIG Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
PVRIG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-55 KDa and the accession number is A0A1B0GS01. | |||
TMPY-06277 | PVRIG Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
PVRIG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.15 kDa and the accession number is Q6DKI7-1. | |||
TMPY-05560 | PVRL1/NECTIN1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
PVRL1/NECTIN1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q9JKF6. | |||
TMPY-06301 | PVRIG Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
PVRIG Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.31 kDa and the accession number is Q6DKI7-1. | |||
TMPY-05165 | PVRIG Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
PVRIG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.9 kDa and the accession number is Q6DKI7. | |||
TMPY-03030 | PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
PVRL1/NECTIN1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.3 kDa and the accession number is A6J3U6. | |||
TMPY-01571 | PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPJ-00629 | TIGIT Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane... | |||
TMPK-00229 | DNAM-1/CD226 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD1... | |||
TMPK-00230 | DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD1... |