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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6266 | PP2 | AGL 1879,AG 1879,AGL 1879 | EGFR , Tyrosine Kinases , JAK , Src |
PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2. | |||
T6266L | PP2 Analog | PP2-Analog,CHEMBL-306012,CHEMBL306012,CHEMBL 306012 | |
PP2 Analog is an analog of PP2. It also acts as a protein trafficking modulator. | |||
T23176 | PP 3 | Src | |
PP 3 is a Negative control for the Src kinase inhibitor PP 2 | |||
T2414 | Torkinib | PP 242 | Apoptosis , Mitophagy , PI3K , mTOR , Autophagy |
Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM). | |||
T2415 | PP121 | Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck | |
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM). | |||
T79878 | Hydroxy-PP-Me | Apoptosis | |
Hydroxy-PP-Me is a potent and specific CBR1 inhibitor, exhibiting an IC50 of 759 nM. It not only inhibits serum-withdrawal-induced apoptosis but also enhances As2O3-induced apoptotic cell death when used in conjunction w... |