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Search Results for " plk4 "

11

Compounds

Cat No. Product Name Synonyms Targets
T22288 (1E)-CFI-400437 dihydrochloride CFI-400437 dihydrochloride PLK
(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.
T7384 Ocifisertib(CFI-400945 free base) PLK
CFI-400945 is an potent, selective and orally active inhibitor of polo-like kinase 4(PLK4; Ki value of 0.26 nM).
T14927 Centrinone LCR-263 PLK , Aurora Kinase
Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).
T1843 XMD8-92 ERK , BMI-1 , Epigenetic Reader Domain
XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).
T14926 Centrinone-B LCR-323 Aurora Kinase
Centrinone-B (LCR-323) is a potent and highly selective inhibitor of PLK4 (Ki: 0.59 nM).
T63318 CFI-400437
CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.
T78728 SP27 PROTACs
SP27, a selective PROTAC, degrades PLK4 with a DC50 of 19.5 nM and may be utilized in breast cancer research [1].
T73471 YLT-11
YLT-11 is a potent, selective, and orally active inhibitor of polo-like kinase 4 (PLK4), exhibiting dissociation constant (Kd) values of >10000 nM for PLK1, 653 nM for PLK2, >10000 nM for PLK3, and 5.2 nM for PLK4, respe...
T82385 FMF-06-098-1 PROTACs
FMF-06-098-1 is a multitargeted depressant capable of promoting the degradation of a wide array of kinases, including AAK1, ABL2, AURKA, AURKB, BUB1B, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDK6, CDK7, CDK9, CHEK1, CSNK1D...
T19664 ON1231320 GBO-006 Apoptosis , PLK
ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.
T74644 DB0614
DB0614 (Example 21) is a bifunctional compound designed for the targeted degradation of kinases, effectively breaking down a wide array of kinases including AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK...
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