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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60108 | PDGFR Tyrosine Kinase Inhibitor III | PDGF Receptor Tyrosine Kinase Inhibitor III | PDGFR |
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF... | |||
T62872 | PDGFR-IN-1 | ||
PDGFR-IN-1 (compound 7m) is an orally active PDGFR (platelet-derived growth factor receptor) inhibitor that acts on PDGFRα (IC50: 2.4 nM) and PDGFRβ (IC50: 0.9 nM). PDGFR-IN-1 exhibits strong anti-tumour effects and low ... | |||
T78843 | MET/PDGFRA-IN-1 | c-Met/HGFR | |
MET/PDGFRA-IN-1 (compound 8c) serves as an inhibitor of MET and PDGFRA proteins, displaying an IC50 of 36 μM against MET. It impedes MET phosphorylation, thereby promoting apoptosis, and curtails the proliferation of var... | |||
T71944 | FGF/PDGF/VEGF RTK Inhibitor | ||
FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of h... | |||
T12396 | PDGFRα kinase inhibitor 1 | PDGFR | |
PDGFRα kinase inhibitor 1 is a highly selective inhibitor of type II PDGFRα kinase (PDGFRα and PDGFRβ with IC50s of 132 nM and 6115 nM , respectively). | |||
T63454 | PDGFRα/FLT3-ITD-IN-1 | ||
PDGFRα/FLT3-ITD-IN-1 are potent inhibitors of PDGFRα/FLT3, and their IC50 values are greater than 0.036 and 0.003 μM, respectively. PDGFRα/FLT3-ITD-IN-1 exhibits investigational potential in acute myeloid leukemia or chr... | |||
T63127 | PDGFRα/FLT3-ITD-IN-3 | ||
PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/FLT3-ITD-IN-3 has the potential to be studied in acute myeloid leukaemia or chronic eosinophilic leuk... | |||
T63629 | PDGFRα/FLT3-ITD-IN-2 | ||
PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM). PDGFRα/FLT3-ITD-IN-2 has shown investigational potential in acute myeloid leukemia or chronic eosinophilic leukemia. | |||
T78844 | MET/PDGFRA-IN-2 | c-Met/HGFR | |
MET/PDGFRA-IN-2 (compound 8h) serves as an inhibitor of MET and PDGFRA proteins, promoting apoptosis in cells and impeding the proliferation of MET-positive cells with IC50 values of 9.7, 6.1, 12.0, 11.5, 8.6, and 34.4 μ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02801 | PHGDH Protein, Human, Recombinant (His) | Human | E. coli |
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPY-04976 | PDGFC Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
PDGFC Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.4 kDa and the accession number is Q8CI19. | |||
TMPJ-00735 | PDGF-BB Protein, Human, Recombinant | Human | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPY-04644 | PDGFB Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-01139 | PDGFRA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1. | |||
TMPK-00421 | PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619. | |||
TMPK-00943 | PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ... | |||
TMPY-05076 | PDGFB Protein, Canine, Recombinant (His) | Canine | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-05075 | PDGFA Protein, Canine, Recombinant (His) | Canine | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera... | |||
TMPK-00481 | PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity ... | |||
TMPK-00420 | PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ... | |||
TMPY-04877 | PDGFB Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-05077 | PDGFB Protein, Rhesus, Recombinant (His) | Rhesus | P. pastoris (Yeast) |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-00269 | PDGFC Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
PDGFC Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is G7P6G9. | |||
TMPY-05358 | PDGFRB Protein, Human, Recombinant | Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1. | |||
TMPY-06921 | PDGFRA Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.68 kDa and the accession number is Q0PW86. | |||
TMPY-05068 | PDGFA Protein, Rat, Recombinant (His) | Rat | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera... | |||
TMPY-04937 | PDGFRB Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1. | |||
TMPY-02251 | PDGFC Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
PDGFC Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q8CI19. | |||
TMPK-00419 | PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ... | |||
TMPH-02835 | PDGFD Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role ... | |||
TMPY-03919 | PDGFRA Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
PDGFRA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number is G3V6A0. | |||
TMPY-02395 | PDGFB Protein, Cynomolgus, Recombinant (mFc) | Cynomolgus | HEK293 Cells |
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit... | |||
TMPY-00900 | PDGFRA Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.9 kDa and the accession number is P16234-1. | |||
TMPY-01207 | PDGFRB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P09619-1. | |||
TMPY-05497 | PDGFRB Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
PDGFRB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number is P09619-1. | |||
TMPY-05056 | PDGFA Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera... | |||
TMPY-03590 | PDGFRB Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
PDGFRB Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is F7BTH1. | |||
TMPY-03474 | PDGFRB Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
PDGFRB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.2 kDa and the accession number is Q05030. | |||
TMPY-03825 | PDGFRA Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
PDGFRA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is A6JD04. | |||
TMPJ-00767 | PDGF-AA Protein, Human, Recombinant | Human | E. coli |
PDGF-AA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P04085. | |||
TMPY-00898 | PDGFC Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
PDGFC Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is Q9NRA1-1. | |||
TMPY-00455 | PDGFA Protein, Canine, Recombinant (hFc) | Canine | HEK293 Cells |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera... | |||
TMPY-04838 | PDGFA Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera... | |||
TMPY-05787 | PDGFRA Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession number is P26618-2. | |||
TMPK-00422 | PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619. | |||
TMPY-05608 | PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 59.4 kDa and the accession number is P16234-1. | |||
TMPJ-00768 | PDGF-AA Protein, Human, Recombinant (His) | Human | E. coli |
PDGF-AA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is P04085. | |||
TMPY-00385 | PDGFRB Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 Cells |
PDGFRB Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.3 kDa and the accession number is F7BTH1. | |||
TMPY-05789 | PDGFRA Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession number is P26618-2. | |||
TMPK-01178 | PDGFD Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, including proliferation, migration, adhesion and tube format... | |||
TMPK-01050 | PDGF R beta/CD140b Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3. | |||
TMPY-03140 | PDGFRB Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q05030. | |||
TMPY-02815 | PDGFC Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
PDGFC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 13.89 kDa and the accession number is Q9NRA1-1. |