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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20571 | Cis-PDA | cis PDA | GluR , NMDAR , iGluR |
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses. | |||
T31792 | Filaminast | UNII-CDD69JC61J,Way-pda-641,WAY-PDA 641,CDD69JC61J | PDE |
Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug. | |||
T33808 | 12-Oxo phytodienoic acid | 12-Oxo-Phytodienoic acid,12-OPDA,12-oxo PDA,OPDA | Others |
12-Oxo phytodienoic acid (12-oxo PDA) is an endogenous signal converter that increases alkaloid biosynthesis in E. californica cell cultures, increases b. dioica tendril curls, And inhibited jasmonic acid-induced program... | |||
T4367 | Mycro 3 | Mycro-3 | c-Myc , Autophagy |
Mycro 3 is potent and selective for c-Myc in whole cell assays. | |||
T18997 | GPDA | Glycylproline p-nitroanilide tosylate,GPN | Others |
GPDA (Glycylproline p-nitroanilide tosylate) is a substrate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay. | |||
T73552 | BPDA2 | ||
BPDA2 is a highly selective and competitive SHP2 inhibitor, exhibiting IC50 values of 92.0 nM for SHP2, and 33.39 μM and 40.71 μM for SHP1 and SHP1B, respectively. This compound effectively downregulates mitogenic and ce... | |||
T79607 | H-NTPDase-IN-2 | hNTPDase-IN-2 | Phosphatase |
h-NTPDase-IN-2 is a broad-spectrum NTPDase inhibitor that inhibits multiple h-NTPDas isoforms. | |||
T79492 | H-NTPDase8-IN-1 | Phosphatase | |
h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8 (IC 50 = 0.28 ± 0.07 μM). h-NTPDase8-IN-1 can be used to study diseases brought about by aberrant h -NTPDase expression. | |||
T10877 | CPDA | Phosphatase | |
CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2). | |||
T79622 | H-NTPDase-IN-3 | Phosphatase | |
h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8. | |||
T77661 | H-NTPDase-IN-4 | Phosphatase | |
h-NTPDase-IN-4 is a pan-inhibitor of NTPDase, which can inhibit h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8. The IC50 values were 3.58 μM, 10.21 μM, 0.13 μM and 13.57 μM, respectively. | |||
TQ0114 | CMPDA | GluR | |
CMPDA is a positive allosteric modulator of AMPA receptors (EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor). | |||
T79491 | H-NTPDase-IN-1 | Phosphatase | |
h-NTPDase-IN-1 (Compound 3i) is an inhibitor of human NTPDase (h-NTPDase) with IC50 values of 2.88 μM for h-NTPDase1 and 0.72 μM for h-NTPDase3, indicating its potential utility for thrombosis, inflammation, diabetes, an... | |||
T62703 | NTPDase-IN-2 | ||
NTPDase-IN-2 (compound 5g) selectively inhibits NTPDase-2 and NTPDase-8 with IC50 values of 0.04 µM and 2.27 µM, respectively, and exhibits non-competitive inhibition towards h-NTPDase-1 and h-NTPDase-2, with a Km of 74 ... | |||
T61377 | NTPDase-IN-1 | ||
NTPDase-IN-1 (compound 5a) is a selective inhibitor of NTPDase enzymes. It shows inhibitory activity against h-NTPDase-1, h-NTPDase-2, and h-NTPDase-8 with IC50 values of 0.05 μM, 0.23 μM, and 0.54 μM, respectively. NTPD... | |||
T62633 | NTPDase-IN-3 | ||
NTPDase-IN-3 (Compound 5e), an inhibitor of NTPDase, exhibits IC50 values of 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2). It is utilized in cancer and thrombosis research [1]. | |||
T24604 | PDAT | Propyl Dimethyl Amino Tryptamine | |
PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor. | |||
T79623 | H-NTPDase-IN-5 | Phosphatase | |
h-NTPDase-IN-5 (compound 3b) serves as a pan-inhibitor of NTPDase, exhibiting inhibitory concentration 50 (IC50) values of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), and 0.32 μM (h-NTPDase8). | |||
T23179 | PPDA | Others | |
Subtype-selective NMDA receptor antagonist | |||
TQ0095 | Brincidofovir | CMX001,HDP-CDV | Others , Antiviral , HSV |
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses. |