20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81546 | PARG-IN-4 | ||
PARG-IN-4 (Formula (A)), an orally active and cell-permeable inhibitor of poly(ADP-ribose) glycohydrolase (PARG), demonstrates effective inhibition of tumor growth in mouse models and is applicable in cancer research [1]... | |||
T83799 | 6-alkyne NAD+ sodium | β-Nicotinamide-N6-propargyladenine dinucleotide,6-Parg NAD,6-alkyne Nicotinamide adenine dinucleotide,Click Tag™ 6-alkyne NAD | |
6-alkyne NAD+, a clickable variant of the signaling molecule and enzyme cofactor NAD+, facilitates the fluorescent tagging for the detection of poly(ADP-ribose) polymerase (PARP) protein substrates. | |||
T1440 | Ethacridine lactate monohydrate | Antibacterial , Antibiotic | |
Ethacridine lactate hydrate is a topically applied anti-infective agent. | |||
T5967 | Ethacridine lactate | Acrinol,6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE | Others , Antibacterial |
Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. | |||
T9389 | Thalidomide-PEG4-Propargyl | Thalidomide-O-PEG4-Propargyl | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1]. | |||
T18560 | Propargyl-C1-NHS ester | 4-Pentynoic Acid Succinimidyl Ester | Others |
Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) is a nonclaevable linker used for antibody-drug-conjugation (ADC). | |||
T12284 | O-Propargyl-Puromycin | OP-puro,O-Propargylpuromycin | Others |
O-Propargyl-Puromycin (OP-puro) is a potent protein synthesis inhibitor, a puromycin acetylene analog. | |||
T39849 | Propargite | Parasite | |
Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC 50 of 1 μM [1] . | |||
T16605 | Propargyl-PEG3-acid | PROTAC Linker | |
Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker. Propargyl-PEG3-acid is also a PEG-based PROTAC linker used to synthesize 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA and Propargyl-PEG3-acid[1]. | |||
T38173 | Propargylcholine | Propargylcholine (bromide) | Antibacterial |
Propargylcholine (Propargylcholine (bromide)) is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa. | |||
T18566 | Propargyl-PEG12-bromide | Others , PROTAC Linker | |
Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | |||
T18588 | Propargyl-PEG5-Ms | Propargyl-PEG6-Ms | Others , PROTAC Linker |
Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) is a PEG-based PROTAC linker. Propargyl-PEG5-Ms can be used in the synthesis of PROTACs. | |||
T16326 | Cipargamin | KAE609,NITD609 | Parasite |
Cipargamin (NITD609) is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum. | |||
T19455 | N-ε-propargyloxycarbonyl-L-lysine hydrochloride | N6-((Prop-2-yn-1-yloxy)carbonyl)-L-lysine hydrochloride,H-L-Lys(Poc)-OH (hydrochloride) | Others |
N-ε-propargyloxycarbonyl-L-lysine hydrochloride (N6-((Prop-2-yn-1-yloxy)carbonyl)-L-lysine hydrochloride) is a modified amino acid for cancer therapy development. | |||
T18831 | Thalidomide-propargyl | Others , Ligand for E3 Ligase | |
Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs. | |||
T1578 | Pargyline hydrochloride | Pargylamine hydrochloride | MAO , Monoamine Oxidase |
Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties. | |||
T20129 | L-Propargylglycine | (S)-Propargylglycine,(S)-alpha.Propargylglycine,Propargylglycine | Others |
L-Propargylglycine ((S)-Propargylglycine) is an inhibitor of the enzyme. | |||
T38079 | DL-Propargylglycine HCl | DL-Propargyl Glycine HCl,DL-Propargyl Glycine hydrochloride | Others |
DL-Propargylglycine HCl (DL-Propargyl Glycine HCl) is a potent irreversible inhibitor of cystathionine γ-cleaving enzyme and can be used in the study of heart failure. | |||
T18574 | Propargyl-PEG17-methane | MPEG16-Propyne | Others , PROTAC Linker |
Propargyl-PEG17-methane (MPEG16-Propyne) is a PEG-based PROTAC linker. Propargyl-PEG17-methane can be used in the synthesis of PROTACs. | |||
T18568 | Propargyl-PEG11-methane | Others , PROTAC Linker | |
Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1]. |