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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2030 | Tiplaxtinin | PAI-039,Tiplasinin | PAI-1 , Apoptosis |
Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM. | |||
T4254 | TM5441 | PAI-1 , Apoptosis | |
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1). | |||
T3442 | UK-371804 | UK371804 | PAI-1 , Serine Protease |
UK-371804 is an effective and specific uPA inhibitor. It was selected as a candidate for further preClinicalal evaluation for the treatment of chronic dermal ulcers. | |||
T8962 | TM5007 | PAI-1 | |
TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM). | |||
T4S0592 | Toddalolactone | (+)-Toddalolactone | PAI-1 |
Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic. | |||
T13257 | Upamostat | PAI-1 , Serine/threonin kinase , Serine Protease | |
Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor. | |||
T3876 | Loureirin B | PAI-1 , ERK , Potassium Channel , JNK | |
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw... | |||
T4255 | TM5275 sodium | TM5275 sodium salt | PAI-1 |
TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1). | |||
T29856 | Aleplasinin | PAZ 417,PAZ417,PAZ-417 | PAI-1 |
Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies... | |||
T13408 | ZK824190 | Others , Serine Protease | |
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively). | |||
T28788 | SK-216 | SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor | |
SK-216 is a specific PAI-1 inhibitor. SK-216 reduced the extent of angiogenesis in the tumors and inhibited VEGF-induced migration and tube formation by human umbilical vein endothelial cells in vitro. SK-216 reduced the... | |||
T23764 | AZ3976 | AZ 3976,AZ-3976 | PAI-1 |
AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities. | |||
T68572 | IMD-1622 | ||
IMD-1622 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor. | |||
T25915 | Diaplasinin | PAI-749,PAI749,PAI 749 | |
PAI-749 is a selective and effective antagonist agent of plasminogen activator inhibitor 1 (PAI-1). | |||
T25217 | CDE-096 | ||
CDE-096 is a plasminogenactivator inhibitor-1 (PAI-1) inactivator. | |||
T70810 | THR-18 | ||
THR-18 is an 18-mer peptide derived from the sequence of human plasminogen activator inhibitor 1 (PAI-1), having the ability to bind to a site of tissue plasminogen activator (tPA) distal to its catalytic site and uncoup... | |||
T35520 | Aflatoxin G1-13C17 | Aflatoxin G1-13C17 | |
Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to duckli... |