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Search Result

Search Results for " p-500 "

Targets

VEGFR PI3K Src mTOR

11

Compounds

3

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6730 WAY-600 WAY600 VEGFR , PI3K , Src , mTOR
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold...
T6732 WYE-687 p38 MAPK , PI3K , Src , mTOR
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fol...
T6731 WYE-354 Apoptosis , PI3K , mTOR , Autophagy
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ ...
T68667 Oxanosine
Oxanosine is an analog of guanosine that has been found in S. capreolus and has diverse biological activities, including antibacterial, antiviral, and anticancer properties. It is active against a variety of bacteria, in...
T35452 β-Defensin-3 (human) (trifluoroacetate salt)
β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T35453 β-Defensin-4 (human) (trifluoroacetate salt)
β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T36729 Urotensin II (goby) (trifluoroacetate salt)
Urotensin II is a peptide vasoconstrictor and agonist of the urotensin (UT) receptor (Ki= 2.06 nM for the human recombinant receptor expressed in HEK293 cells).1It stimulates intracellular calcium mobilization in HEK293 ...
T36401 DCVC
DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Target: TNF-αin vitro: DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhib...
T36629 Givinostat
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30...
T36648 Tucatinib hemiethanolate
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-f...
T35451 β-Defensin-2 (human) (trifluoroacetate salt)
β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...
Cat No. Product Name Synonyms Targets
TN4883 Quinine sulfate dihydrate Others
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu...
T38086 Neohydroxyaspergillic Acid
Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. my...
T36886 Pestalotin
Pestalotin is a fungal metabolite originally isolated from P. cryptomeriaecola with diverse biological activities. It induces reducing sugar release in embryoless rice endosperms when used at concentrations ranging from ...

Natural Products

Quinine sulfate dihydrate
TN4883
Synonym:
Target: Others
Neohydroxyaspergillic Acid
T38086
Synonym:
Target:
Pestalotin
T36886
Synonym:
Target:

Recombinant Proteins

Species：
Human (2)
Expression System：
E. coli (1)
HEK293 Cells (1)
Tag：
Tag Free (1)
hFc (1)
Cat No. Product Name Species Expression System
TMPY-00695 I-309 Protein, Human, Recombinant (hFc) Human HEK293 Cells
I-309 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is P22362.
TMPY-03071 I-309 Protein, Human, Recombinant Human E. coli
I-309 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.7 kDa and the accession number is P22362.
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