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Search Results for " nrti "

17

Compounds

Cat No. Product Name Synonyms Targets
T14489 Azvudine FNC,RO-0622 HCV Protease , HBV , HIV Protease , Reverse Transcriptase
Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1...
T78948 NNRTIs-IN-1
NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-type HIV-1 and five mutant strains at EC50 values within the nano...
T78737 NNRTIs-IN-3 HIV Protease
NNRTIs-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor, displaying potent efficacy with an EC50 value of 0.01 µM [1].
T0110 Zalcitabine Dideoxycytidine,ddC,NSC 606170,Ro 24-2027/000,2',3'-Dideoxycytidine HIV Protease , Reverse Transcriptase
Zalcitabine (Dideoxycytidine)(Dideoxycytidine;ddC; 2', 3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently inhibit HIV replication by binding to rever...
T2409 Tenofovir alafenamide GS-7340 HIV Protease , Reverse Transcriptase
Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.
T2279 Tizoxanide Desacetyl-nitazoxanide,TIZ Antiviral , HIV Protease , Antibacterial , Autophagy
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
T6214 Emtricitabine FTC,Emtriva,BW1592 HIV Protease , Reverse Transcriptase
Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus.
T38727 Azvudine hydrochloride RO-0622 hydrochloride,Azvudine hydrochloride,FNChydrochloride
Azvudine hydrochloride (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI) that exhibits strong antiviral effects against HIV, HBV, and HCV. It demonstrates highly potent inhibition of HIV-1 (EC 50 ra...
T71518 Zidovudine diphosphate
Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptas...
T64188 FNC-TP trisodium
FNC-TP trisodium is the intracellularly active form of FNC, a potent inhibitor of nucleoside reverse transcriptase (NRTI) that exhibits antiviral effects against HIV, HBV and HCV.
T71241 Carbovir
Carbovir, also known as (-)-Carbovir, is a nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) caused mitochondrial toxicity in human hepatoma carcinoma cell.
T61427 Lamivudine salicylate
Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI) that effectively inhibits the reverse transcriptase activity of both HIV 1/2 and hepatitis B virus. Moreover, it demon...
T14488 Azt-pmap HIV Protease
AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1]. As a nucleoside reverse transcriptase inhibitor (NRTI), AZT-PMPA targets HIV infection effectively[2].
T40120 FNC-TP
FNC-TP, the intracellular active form of FNC, is a potent nucleoside reverse transcriptase inhibitor (NRTI) with broad-spectrum antiviral activity against HIV, HBV, and HCV.
T60356 Stavudine sodium
Stavudine sodium (d4T), an orally active nucleoside reverse transcriptase inhibitor (NRTI), demonstrates activity against both HIV-1 and HIV-2. It also inhibits mitochondrial DNA (mtDNA) replication, reduces NLRP3 inflam...
T71983 Zidovudine glucuronide
Zidovudine glucuronide is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptas...
T24839 Stampidine HI-113,HI 113,HI113
Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical...
TargetMol