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Search Result

Search Results for " npy "

Targets

Neuropeptide Y Receptor

66

Compounds

14

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T23087 NPY 5RA972 Neuropeptide Y Receptor
neuropeptide Y Y5 receptor antagonist
TP2194L Neuropeptide Y (scrambled) Acetate Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate Others
Neuropeptide Y (scrambled) Acetate (Pro-Neuropeptide Y (scrambled) Acetate) is a scrambled peptide of Neuropeptide Y that has been implicated in Alzheimer's disease (AD) and may have neuroprotective effects.
T83677 Neuropeptide Y (porcine, bovine) TFA NPY (porcine, bovine)
Neuropeptide Y (NPY), a neuropeptide, plays roles in regulating appetite, vasoconstriction, cardiac contractility, and intestinal secretion, acting as an agonist for NPY receptors Y1, Y2, and Y5. Expressed ubiquitously, ...
T71749 SF-22 Neuropeptide Y Receptor
SF-22 is a neuropeptide Y receptor (Y2R) antagonist that crosses the blood-brain barrier and has potential anti-inflammatory activity for the study of diseases associated with neurological disorders.
T23094 NTNCB hydrochloride Others , Neuropeptide Y Receptor
NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.
TQ0286 MK-0557 Neuropeptide Y Receptor
MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).
TP2206 [Leu31,Pro34]-Neuropeptide Y (porcine) Neuropeptide Y Receptor
High affinity neuropeptide Y Y1 receptor agonist
T10539 BIBO3304 TFA Neuropeptide Y Receptor
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor).
T8963 CYM2503 Neuropeptide Y Receptor
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by ...
T17222 Velneperit S2367 Neuropeptide Y Receptor
Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
T5455 HT-2157 SNAP37889,SNAP-37889 Neuropeptide Y Receptor
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
T5587 CGP71683 hydrochloride CGP71683A Neuropeptide Y Receptor
CGP71683 hydrochloride (CGP71683A) is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
T1997 JNJ-31020028 JNJ 31020028 Neuropeptide Y Receptor
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
TP1380 Galanin (1-16), mouse, porcine, rat Neuropeptide Y Receptor
Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.
TP1059 Peptide YY (PYY) (3-36), human Peptide YY (3-36) Neuropeptide Y Receptor
Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.
T8456 GALNON Neuropeptide Y Receptor
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
T12895 SHA 68 Neuropeptide Y Receptor
SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR)(NPSR Asn107 and NPSR Ile107 with IC50s of 22.0 and 23.8 nM, respectively).
T4445 Tolfenpyrad Antibacterial
Tolfenpyrad is an effective insecticide[1], used against pests that are resistant to existing insecticides such as organophosphates and carbamates.[2]
T0435 Sulfinpyrazone (+/-)-Sulfinpyrazone,G-28315,NSC 75925 COX
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
T8692 (Rac)-Benpyrine TNF
(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.
T4446 Tebufenpyrad Pyranica,MK239,Comanche Mitochondrial Metabolism
Tebufenpyrad (Comanche) (mitochondrial complex-1 inhibitors) is an agro-chemically important acaricide that functions like the known mitochondrial toxicant rotenone.
T6607 Nitenpyram Niterndipoine,Bestguard,Capstar AChR
Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.
T19714 Fenpyroximate Others
Fenpyroximate is an acaricide and insecticide. It blocking the mitochondrial electron transport in complex I.
TP1963 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM)...
T33968 Phenchlobenpyrrone
Phenchlobenpyrrone has potential as a treatment for Alzheimer's disease.
T75913 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent, selective neuropeptide Y Y5 receptor agonist, demonstrating binding affinity with an IC50 of 0.24 nM for the hY5 receptor. This compound significan...
T38763 Mefenpyr-diethyl
Mefenpyr-diethyl is an herbicide safener, which protects crops against herbicide injury.
T76553 TAT (47-57) GGG-Cys(Npys)
TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP) with potential applications in intracellular drug delivery research [1].
T76545 Cys(Npys)-TAT (47-57)
Cys(Npys)-TAT (47-57), a peptide fragment corresponding to the transduction domain of the TAT peptide, features an activated cysteine residue C and is capable of electrostatically interacting with plasmid DNA. Notably, T...
T36486 Benpyrine
Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the poten...
T21611L BWX 46 Acetate BWX 46 Acetate(172997-92-1 Free base) Neuropeptide Y Receptor
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM.
TP1044L Pancreatic Polypeptide, rat acetate Neuropeptide Y Receptor
Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.
T24121 GW438014A GW 438014 A,GW-438014-A Neuropeptide Y Receptor
GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.
TP1984L [D-Trp34]-Neuropeptide Y Acetate [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base) Neuropeptide Y Receptor
[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-...
TP1618L PACAP-38 (31-38), human, mouse, rat acetate PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base) PACAP
PACAP-38 (31-38), human, mouse, rat acetate is an activator of PAC1 receptor. PACAP-38 (31-38), human, mouse, rat acetate demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY an...
TP1137L Pancreatic Polypeptide (human) acetate Neuropeptide Y Receptor
Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
T26800 BIBO3304 BIBO-3304,BIBO 3304
BIBO3304 is a selective NPY Y1 receptor antagonist (IC50 values are 0.38 and 0.72 nM at human and rat receptors respectively). BIBO3304 inhibits NPY- and fasting-induced feeding in vivo following central administration.
T29171 Y2 Antagonist 36
Y2 Antagonist 36 is a highly potent, soluble and selective antagonist of NPY Y2.
TP2194 Neuropeptide Y (scrambled) Others
Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiologi...
T35599 Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY (3-36) is an endogenous peptide produced ...
T71091 Y2-Antagonist-2
Y2-Antagonist-2 is a novel, selective, soluble non-peptidic NPY Y2 receptor antagonist with enhanced CNS exposure.
T70952 UR-MK299
UR-MK299 is a NPY Y1 receptor antagonist.
T69220 GW438014 free base
GW438014A is a selective NPY-Y5 receptor antagonist.
T22935 LU AA33810 Others
LU AA33810 is a neuropeptide Y (NPY) Y5 receptor antagonist.
T23287 S 25585 Others
S 25585 is a neuropeptide Y (NPY) Y5 receptor antagonist.
T14572 BIIE-0246 AR-H 053591 Others
BIIE-0246 is a potent and highly selective non-peptide neuropeptide Y (NPY) Y2 receptor antagonist. With an IC50 of 15 nM.
TP2215 Agouti-related Protein (AGRP) (25-82), human Others
Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalam...
TP1619 PACAP-38 (16-38), human, mouse, rat
PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production.
T70061 CGP 71683 (free base)
CGP 71683 (free base) is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.
T74654 Neuropeptide Y5 receptor ligand-1
Neuropeptide Y5 receptor ligand-1 (Compound 54), a carbazole derivative, acts as a powerful antagonist to the neuropeptide Y5 (NPY-5) receptor [1].

Compounds

NPY 5RA972
T23087
Synonym:
Target: Neuropeptide Y Receptor
Neuropeptide Y (scrambled) Acetate
TP2194L
Synonym: Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate
Target: Others
Neuropeptide Y (porcine, bovine) TFA
T83677
Synonym: NPY (porcine, bovine)
Target:
SF-22
T71749
Synonym:
Target: Neuropeptide Y Receptor
NTNCB hydrochloride
T23094
Synonym:
Target: Others, Neuropeptide Y Receptor
MK-0557
TQ0286
Synonym:
Target: Neuropeptide Y Receptor
[Leu31,Pro34]-Neuropeptide Y (porcine)
TP2206
Synonym:
Target: Neuropeptide Y Receptor
BIBO3304 TFA
T10539
Synonym:
Target: Neuropeptide Y Receptor
CYM2503
T8963
Synonym:
Target: Neuropeptide Y Receptor
Velneperit
T17222
Synonym: S2367
Target: Neuropeptide Y Receptor
HT-2157
T5455
Synonym: SNAP37889,SNAP-37889
Target: Neuropeptide Y Receptor
CGP71683 hydrochloride
T5587
Synonym: CGP71683A
Target: Neuropeptide Y Receptor
JNJ-31020028
T1997
Synonym: JNJ 31020028
Target: Neuropeptide Y Receptor
Galanin (1-16), mouse, porcine, rat
TP1380
Synonym:
Target: Neuropeptide Y Receptor
Peptide YY (PYY) (3-36), human
TP1059
Synonym: Peptide YY (3-36)
Target: Neuropeptide Y Receptor
GALNON
T8456
Synonym:
Target: Neuropeptide Y Receptor
SHA 68
T12895
Synonym:
Target: Neuropeptide Y Receptor
Tolfenpyrad
T4445
Synonym:
Target: Antibacterial
Sulfinpyrazone
T0435
Synonym: (+/-)-Sulfinpyrazone,G-28315,NSC 75925
Target: COX
(Rac)-Benpyrine
T8692
Synonym:
Target: TNF
Tebufenpyrad
T4446
Synonym: Pyranica,MK239,Comanche
Target: Mitochondrial Metabolism
Nitenpyram
T6607
Synonym: Niterndipoine,Bestguard,Capstar
Target: AChR
Fenpyroximate
T19714
Synonym:
Target: Others
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide
TP1963
Synonym: cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
Target:
Phenchlobenpyrrone
T33968
Synonym:
Target:
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA
T75913
Synonym:
Target:
Mefenpyr-diethyl
T38763
Synonym:
Target:
TAT (47-57) GGG-Cys(Npys)
T76553
Synonym:
Target:
Cys(Npys)-TAT (47-57)
T76545
Synonym:
Target:
Benpyrine
T36486
Synonym:
Target:
BWX 46 Acetate
T21611L
Synonym: BWX 46 Acetate(172997-92-1 Free base)
Target: Neuropeptide Y Receptor
Pancreatic Polypeptide, rat acetate
TP1044L
Synonym:
Target: Neuropeptide Y Receptor
GW438014A
T24121
Synonym: GW 438014 A,GW-438014-A
Target: Neuropeptide Y Receptor
[D-Trp34]-Neuropeptide Y Acetate
TP1984L
Synonym: [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)
Target: Neuropeptide Y Receptor
PACAP-38 (31-38), human, mouse, rat acetate
TP1618L
Synonym: PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)
Target: PACAP
Pancreatic Polypeptide (human) acetate
TP1137L
Synonym:
Target: Neuropeptide Y Receptor
BIBO3304
T26800
Synonym: BIBO-3304,BIBO 3304
Target:
Y2 Antagonist 36
T29171
Synonym:
Target:
Neuropeptide Y (scrambled)
TP2194
Synonym:
Target: Others
Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
T35599
Synonym:
Target:
Y2-Antagonist-2
T71091
Synonym:
Target:
UR-MK299
T70952
Synonym:
Target:
GW438014 free base
T69220
Synonym:
Target:
LU AA33810
T22935
Synonym:
Target: Others
S 25585
T23287
Synonym:
Target: Others
BIIE-0246
T14572
Synonym: AR-H 053591
Target: Others
Agouti-related Protein (AGRP) (25-82), human
TP2215
Synonym:
Target: Others
PACAP-38 (16-38), human, mouse, rat
TP1619
Synonym:
Target:
CGP 71683 (free base)
T70061
Synonym:
Target:
Neuropeptide Y5 receptor ligand-1
T74654
Synonym:
Target:
1 2

Recombinant Proteins

Species：
Human (8)
Mouse (6)
Expression System：
HEK293 Cells (10)
E. coli (3)
P. pastoris (Yeast) (1)
Tag：
C-His (5)
C-6xHis (2)
C-hFc (2)
N-10xHis (2)
N-hFc (2)
N-10xHis, C-Myc (1)
Cat No. Product Name Species Expression System
TMPJ-00007 NPY Protein, Human, Recombinant (His) Human HEK293 Cells
Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY ...
TMPH-02843 NPY Protein, Mouse, Recombinant (hFc) Mouse P. pastoris (Yeast)
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
TMPH-01767 NPY2R Protein, Human, Recombinant (His) Human E. coli
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY a...
TMPY-00226 CNPY3 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
CNPY3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.9 kDa and the accession number is Q9DAU1-1.
TMPY-03261 CNPY2 Protein, Human, Recombinant (His) Human HEK293 Cells
CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light cha...
TMPY-00138 CNPY3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
CNPY3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.7 kDa and the accession number is Q9BT09-1.
TMPY-05005 CNPY3 Protein, Human, Recombinant (His) Human HEK293 Cells
CNPY3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is A0A7U3JW12.
TMPH-02847 CNPY2 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.
TMPY-04918 CNPY4 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CNPY4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q8BQ47.
TMPH-02809 NPY2R Protein, Mouse, Recombinant (His) Mouse E. coli
Receptor for neuropeptide Y and peptide YY. NPY2R Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 11.0 kDa and the accession number is P972...
TMPY-00596 CNPY3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CNPY3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q9DAU1-1.
TMPY-03179 CNPY4 Protein, Human, Recombinant (His) Human HEK293 Cells
CNPY4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is Q8N129.
TMPY-00286 Neuropeptide Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPJ-00743 PPY Protein, Human, Recombinant (His) Human HEK293 Cells
PPY belongs to the NPY family and is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknow...
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