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Search Result

Search Results for " ngal "

Targets

Antifungal Antibacterial Antifungal

71

Compounds

2

Natural Products

5

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T9274 Antifungal-agent-6 N-(2-BENZO[1,3]DIOXOL-5-YL-ETHYL)-2-(4-METHYL-BENZYL)-SUCCINAMIC ACID Antibacterial , Antifungal
Antifungal agent 6 shows antifungal activity.
T7651 Rose Bengal sodium Rose Bengal Influenza Virus , Monoamine Transporter
Rose Bengal sodium is a potent inhibitor of VGlut and vesicular monoamine transporter (VMAT) (Ki of 19 and 64 nM for VGlut andVMAT, respectively）
T61257 Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).
T61308 Antifungal agent 27
Antifungal agent 27 (compound 7) is a chemical compound possessing antifungal properties. It exhibits moderate antibacterial activity and weak antifungal activity against MRSA and C. albicans SS5314, with minimal inhibit...
T62098 Antifungal agent 28
Antifungal agent 28 (compound 18) is a selective and potent antifungal agent that disrupts mature Candida biofilms and inhibits pathogenic strains of Candida albicans and non-Candida albicans, including fluconazole-resis...
T74537 Antifungal agent 26
Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1].
T83067 Antifungal agent 81
Antifungal agent 81(G22) exhibits excellent antifungal properties, demonstrating an in vitro IC50 value of 0.48 mg/L against Valsa mali. Moreover, it also shows robust in vivo protection against V. mali at a concentratio...
T83071 Antifungal agent 62
Compound 3a (Antifungal agent 62) exhibits potent fungicidal properties, particularly against Fusarium oxysporum f.sp. cucumerinum, and is utilized in antiviral and fungicidal research [1].
T62658 Antifungal agent 22
Antifungal agent 22 (compound D16) is an orally active, potentially antifungal agent (IC50: 0.5 μg/mL) with blood-brain barrier permeability, good metabolic stability and low cytotoxicity. Antifungal agent 22 is a select...
T79550 Antifungal agent 68
Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol biosynthesis, likely via interaction with lanosterol 14α-demethylase ...
T74976 Antifungal agent 46 Ras
Compound 2f (Antifungal Agent 46) is a potent antifungal that inhibits Ras signaling by targeting protein farnesyltransferase [1].
T79522 Antifungal agent 65
Compound 5d (Antifungal Agent 65) exhibits potent fungicidal activity against Fusarium oxysporum f.sp. cucumerinum and is utilized in antiviral and fungicidal research [1].
T79087 Antifungal agent 59
Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, while maintaining safety [1].
T75177 Antifungal agent 54
Antifungal agent 54 (compound A05) serves as a potent inhibitor against Fluconazole-resistant strains, outperforming Miconazole in efficacy. It exhibits considerable activity against Candida albicans, with minimum inhibi...
T75180 Antifungal agent 57
Antifungal Agent 57 (Compound A19) demonstrates potent efficacy against Fluconazole-resistant strains, outperforming Miconazole. It effectively inhibits Candida albicans strains, exhibiting minimum inhibitory concentrati...
T74772 Antifungal agent 47
Antifungal agent 47 (compound 3b) exhibits the most potent and broad-spectrum fungicidal properties, including significant inhibition of respiration and adenosine 5′-triphosphate synthesis, showcasing its potential as an...
T74220 Antifungal agent 21
Antifungal Agent 21 presents as a promising candidate within the development of novel agrochemical antifungal agents.
T75181 Antifungal agent 58
Antifungal agent 58 (compound A21) exhibits high potency against Fluconazole-resistant strains and outperforms Miconazole in effectiveness. It inhibits Candida albicans strains with minimum inhibitory concentration (MIC)...
T74272 Antifungal agent 84
Antibacterial Agent 84, an antifungal compound, effectively inhibits candidiasis through a CNB1-dependent mechanism and reduces the viability of the C. albicans biofilm [1].
T74959 Antifungal agent 41
Antifungal Agent 41 (compound B01), an effective inhibitor of Candida albicans both in vitro and in vivo, is a potential research tool for invasive fungal infections [1].
T79521 Antifungal agent 64
Compound 5c (Antifungal agent 64) exhibits potent fungicidal activity against Fusarium oxysporum f.sp. cucumerinum and is applicable for research in antiviral and fungicidal domains [1].
T79589 Antifungal agent 71
Antifungal agent 71 (compound 6r), a trifluoromethyl pyrimidine derivative, displays potent in vitro activity against F. oxysporum, evidenced by an EC 50 value of 3.61 μg/mL [1].
T79298 Antifungal agent 61
Antifungal Agent 61 (Compound 38) is an antifungal agent that inhibits V. mali, with an EC50 value of 0.50 mg/L. This compound impedes V. mali's growth by inducing cell deformation and contraction, diminishing intracellu...
T79384 Antifungal agent 72
Antifungal agent 72 (Compound B8) demonstrates potent activity by inhibiting the efflux pump function and downregulating resistance-associated genes via disruption of the Pdr1-KIX interaction (K i : 11.7 μM). It exhibits...
T78893 Antifungal agent 78
Antifungal agent 78 (compound 25am) exhibits potent activity, with an EC50 of 13.46 μM against Fusarium graminearum [1].
T62635 Antifungal agent 30
Antifungal agent 30 is a potent antifungal agent that exhibits good antifungal activity against Candida albicans (CPCC400616) (MIC: 0.03 μg/mL) and Aspergillus fumigatus (MIC: 0.5 μg/mL). Antifungal agent 30 exerts antif...
T60320 Antifungal agent 36
Antifungal agent 36 is a potent anti-fungal agent that shows anti-fungal activity for Basidiomycetes [1].
T40262 Antifungal agent 15
Antifungal agent 15 exhibits remarkable potency, with EC50 values of 0.52 and 0.50 μg/mL against S. sclerotiorum and B. cinerea, respectively.
T62419 Antifungal agent 13
Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.
T74273 Antifungal agent 52
Antifungal agent 52 (compound 6c), a tetrazole derivative, inhibits ergosterol synthesis and significantly exhibits antifungal activity against Candida albicans by affecting the permeabilization of the C. albicans sessil...
T83068 Antifungal agent 77
Antifungal agent 77 (Compound 13h) exhibits not only antifungal properties, but also effective insecticidal activity against Mythimna separata, Helicoverpa armigera, Ostrinia nubilalis, and Spodoptera frugiperda, with mo...
T40329 Antifungal agent 14
Antifungal agent 14 demonstrates potent broad-spectrum antifungal activity, effectively targeting a variety of fungal strains with exceptional minimum inhibitory concentration values.
T60236 Antifungal agent 38
Antifungal agent 38 is a geterocyclic disulfide with antifungal and antibacterial activity. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and le...
T62280 Antifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).
T83066 Antifungal agent 82
Antifungal agent 82 (compound G34) demonstrates outstanding in vitro antifungal efficacy against Valsa mali, exhibiting an EC50 value of 0.57 μg/mL, and has also shown excellent in vivo protective effects at a concentrat...
T83069 Antifungal agent 75
Antifungal agent 75 (compound 6r) effectively combats Candida albicans by substantially inhibiting biofilm formation, enhancing cell membrane permeability, diminishing membrane ergosterol levels, impairing membrane struc...
T83070 Antifungal agent 63
Compound 3i (Antifungal agent 63) is a fungicidal agent displaying potent activity against Fusarium oxysporum f.sp. cucumerinum and has applications in antiviral and fungicidal research [1].
T64235 Antifungal agent 25
Antifungal agent 25 is an effective, broad-spectrum, metabolically stable antifungal agent in vivo. antifungal agent 25 exhibits antifungal effects against both Candida albicans and fluconazole-resistant Candida albicans...
T63285 Antifungal agent 40
Antifungal agent 40 is an antifungal agent that extends into the narrow hydrophobic pocket II of C. alb. CYP51 and inhibits the activity of lanosterol 14α-demethylase (CYP51), which has an inhibitory effect on biofilm fo...
T74526 Antifungal agent 29
Antifungal Agent 29 (compound 9d) is a potent, selective, and non-toxic agent effective against Cryptococcus neoformans, exhibiting an MIC of ≤0.23 μM [1].
T75179 Antifungal agent 56
Antifungal agent 56 (compound A09) is a potent antifungal agent, demonstrating superior efficacy against Fluconazole-resistant strains and outperforming Miconazole. It effectively inhibits Candida albicans strains, with ...
T75178 Antifungal agent 55
Antifungal agent 55 (Compound A07) effectively inhibits Fluconazole-resistant strains of Candida albicans, demonstrating greater efficacy than Miconazole. It exhibits minimum inhibitory concentrations (MIC) values rangin...
T79545 Antifungal agent 66
Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects on the spores of B. cinerea, with an IC50 value of 47.7 μg/mL ...
T78116 Antifungal agent 49
Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].
T10333 Antifungal agent 1 Others
Antifungal agent 1 is an effective antifungal agent.
T62823 Antifungal agent 39
Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.
T61502 Antifungal agent 32
Antifungal agent 32 (compound 1a) is a highly effective antifungal compound. It displays strong inhibitory activity against Candida albicans filamentation and biofilm formation, as well as inhibiting the morphological sw...
T62159 Antifungal agent 24
Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).
T10334 Antifungal agent 2 Others
Antifungal agent 2 is a broad-spectrum fungal inhibitor that inhibits the growth of pertinent species of Cryptococcus, Candida, and Aspergillus at a concentration as low as 0.5 μg/mL.
T63157 Antifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.

Compounds

antifungal-agent-6
T9274
Synonym: N-(2-BENZO[1,3]DIOXOL-5-YL-ETHYL)-2-(4-METHYL-BENZYL)-SUCCINAMIC ACID
Target: Antibacterial, Antifungal
Rose Bengal sodium
T7651
Synonym: Rose Bengal
Target: Influenza Virus, Monoamine Transporter
Antifungal agent 19
T61257
Synonym:
Target:
Antifungal agent 27
T61308
Synonym:
Target:
Antifungal agent 28
T62098
Synonym:
Target:
Antifungal agent 26
T74537
Synonym:
Target:
Antifungal agent 81
T83067
Synonym:
Target:
Antifungal agent 62
T83071
Synonym:
Target:
Antifungal agent 22
T62658
Synonym:
Target:
Antifungal agent 68
T79550
Synonym:
Target:
Antifungal agent 46
T74976
Synonym:
Target: Ras
Antifungal agent 65
T79522
Synonym:
Target:
Antifungal agent 59
T79087
Synonym:
Target:
Antifungal agent 54
T75177
Synonym:
Target:
Antifungal agent 57
T75180
Synonym:
Target:
Antifungal agent 47
T74772
Synonym:
Target:
Antifungal agent 21
T74220
Synonym:
Target:
Antifungal agent 58
T75181
Synonym:
Target:
Antifungal agent 84
T74272
Synonym:
Target:
Antifungal agent 41
T74959
Synonym:
Target:
Antifungal agent 64
T79521
Synonym:
Target:
Antifungal agent 71
T79589
Synonym:
Target:
Antifungal agent 61
T79298
Synonym:
Target:
Antifungal agent 72
T79384
Synonym:
Target:
Antifungal agent 78
T78893
Synonym:
Target:
Antifungal agent 30
T62635
Synonym:
Target:
Antifungal agent 36
T60320
Synonym:
Target:
Antifungal agent 15
T40262
Synonym:
Target:
Antifungal agent 13
T62419
Synonym:
Target:
Antifungal agent 52
T74273
Synonym:
Target:
Antifungal agent 77
T83068
Synonym:
Target:
Antifungal agent 14
T40329
Synonym:
Target:
Antifungal agent 38
T60236
Synonym:
Target:
Antifungal agent 17
T62280
Synonym:
Target:
Antifungal agent 82
T83066
Synonym:
Target:
Antifungal agent 75
T83069
Synonym:
Target:
Antifungal agent 63
T83070
Synonym:
Target:
Antifungal agent 25
T64235
Synonym:
Target:
Antifungal agent 40
T63285
Synonym:
Target:
Antifungal agent 29
T74526
Synonym:
Target:
Antifungal agent 56
T75179
Synonym:
Target:
Antifungal agent 55
T75178
Synonym:
Target:
Antifungal agent 66
T79545
Synonym:
Target:
Antifungal agent 49
T78116
Synonym:
Target:
Antifungal agent 1
T10333
Synonym:
Target: Others
Antifungal agent 39
T62823
Synonym:
Target:
Antifungal agent 32
T61502
Synonym:
Target:
Antifungal agent 24
T62159
Synonym:
Target:
Antifungal agent 2
T10334
Synonym:
Target: Others
Antifungal agent 16
T63157
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T3747 Syringaldehyde Syringic aldehyde,Springaldehyde COX
syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehyde moderately inhibits COX-2 activity wi...
TQ0072 Warangalone Scandenolone PKA
Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively.

Natural Products

syringaldehyde
T3747
Synonym: Syringic aldehyde,Springaldehyde
Target: COX
Warangalone
TQ0072
Synonym: Scandenolone
Target: PKA

Recombinant Proteins

Species：
Human (2)
Aspergillus giganteus (1)
Cynomolgus (1)
Mouse (1)
Expression System：
HEK293 Cells (4)
E. coli (1)
Tag：
C-His (2)
C-hFc (2)
N-6xHis-B2M (1)
Cat No. Product Name Species Expression System
TMPY-00873 Lipocalin-2/LCN2 Protein, Human, Recombinant (His) Human HEK293 Cells
Lipocalin-2/LCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P80188-1.
TMPK-01289 NGAL/Lipocalin-2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
NGAL/Lipocalin-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.51 kDa and the accession number is XP_005580845.3.
TMPK-00085 NGAL/Lipocalin-2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
NGAL/Lipocalin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 47.2 kDa and the accession number is P80188-1.
TMPJ-00082 NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes w...
TMPH-00121 Antifungal Protein, Aspergillus giganteus, Recombinant (B2M & His) Aspergillus giganteus E. coli
This protein inhibits the growth of a variety of fungal species. Antifungal Protein, Aspergillus giganteus, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular ...
Cat No. Product Name
L6001 Mini Fungal Metabolite Natural Product Screening Library

Inquiry
L4500 Anti-Fungal Compound Library

252 compounds
A unique collection of 252 antifungal compounds effective for drug repurposing screening, combination screening and biological investigation.

Libraries

Mini Fungal Metabolite Natural Product Screening Library
L6001
Compounds: Inquiry
Anti-Fungal Compound Library
L4500
Compounds: 252
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