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Search Results for " nf-e1 "

Targets

3

Compounds

2

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T16974 TAK-243 MLN7243 Apoptosis , E1/E2/E3 Enzyme , NF-κB
TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM). TAK-243 blocks ubiquitin binding and disrupts mono-ubiquitin signaling as well as overall protein ubiquitination. TAK-243 exh...
T25465 GS143 GS-143,GS 143 IκB/IKK , E1/E2/E3 Enzyme , NF-κB
GS143 is a selec­tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup­presses NF-κB acti­va­tion and tran­scrip­tion of tar­get genes and does not inhibit protea...
T78750 NF-κB-IN-10 NF-κB
NF-κB-IN-10 (compound E1) is an inhibitor of NF-κB that mitigates heart failure symptoms through the modulation of the Nrf2/NF-κB signaling pathway, alleviating oxidative stress and inflammation. It suppresses LPS-induce...
Cat No. Product Name Synonyms Targets
T2947 Indole-3-carbinol I3C,3-Indolemethanol,Indole-3-Methanol E1/E2/E3 Enzyme , NF-κB , Aryl Hydrocarbon Receptor , Endogenous Metabolite , p53
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.
T5S2129 Sciadopitysin TNF , NF-κB
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00914 YY1 Protein, Human, Recombinant (His) Human E. coli
Transcriptional repressor protein YY1(YY1)contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number...
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