20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T83693 | Magainin 2 TFA | MG2 | |
Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pne... | |||
T10300 | AMG2850 | TRP/TRPV Channel | |
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8). | |||
T69987 | AMG2504 | ||
AMG2504 is a TRPA1 inhibitor. | |||
T15274 | FEN1-IN-1 | LNT-1 | Others |
FEN1-IN-1 (LNT-1) is an inhibitor of flap endonuclease 1 (FEN1). FEN1-IN-1 binds to the active site of FEN1. It partly achieves inhibition by the co-ordination of Mg2+ ions. | |||
T6245 | BAPTA-AM | BAPTA/AM | Potassium Channel |
BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 μM). BAPTA-AM has a 105-fold higher affinity for Ca2+ than for Mg2+, and can be used for... | |||
T7098 | BAPTA | Reactive Oxygen Species | |
BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator. | |||
T3952 | TPEN | TPEDA | Apoptosis , Reactive Oxygen Species , Autophagy |
TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. | |||
T8270 | Deserpidine | Harmonyl | RAAS |
Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie... | |||
T4585 | EGTA | Ethylenebis(oxyethylenenitrilo)tetraacet | Others |
Ethylenebis(oxyethylenenitrilo)tetraacet is a diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively. | |||
T7097 | Cytochalasin B | Phomin | Arp2/3 Complex |
Cytochalasin B is a mycotoxin binding to the barbed end of actin filaments. It can disrupt the formation of actin polymers (Kd: 1.4-2.2 nM for F-actin). | |||
T83941 | Mag-Fura-2 AM | ||
Mag-Fura-2 AM, a cell-permeable fluorescent compound, serves as a selective indicator for magnesium ions (Mg2+), demonstrating significant preference for Mg2+ over other bivalent ions including zinc (Zn2+), copper (Cu2+)... | |||
T20957 | BAPTA Tetrasodium | BAPTA-Na4,BAPTA Na4,BAPTANa4 | |
BAPTA Tetrasodium is a selective fluorescent chelator for calcium. In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg2+. | |||
T40948 | KMG-104 | ||
KMG-104 is a fluorescent magnesium (Mg2+) probe known for its exceptional selectivity. It has been extensively utilized to investigate the mobilization of Mg2+ in the cytoplasm across different cell types. | |||
T83851 | Tat-QFNP12 TFA | ||
Tat-QFNP12 is a peptide that combines a transcriptional transactivator (Tat) transmembrane domain with an inhibitor targeting the interaction between N-Myc downstream regulated gene 2 (NDRG2) and protein phosphatase Mg2+... | |||
T35923 | Caloxin 2A1 TFA | ||
Caloxin 2A1 TFA is a peptide inhibitor specifically targeting the extracellular plasma membrane Ca2+-ATPase (PMCA), without influencing the basal activities of Mg2+-ATPase or Na+-K+-ATPase[1]. | |||
T81882 | Mag-Indo-1 tetrapotassium salt | ||
Mag-Indo-1 tetrapotassium salt is a cell-impermeable fluorescent probe designed for detecting Mg2+ [1]. | |||
T71806 | Tenellin | ||
Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells. | |||
T13618 | Citreoviridin | Others | |
Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas, in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-depen... | |||
T38609 | Mycalolide B | ||
Mycalolide-B is a marine sponge-derived compound that functions as a selective inhibitor of actomyosin ATPase. It effectively hinders ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+. | |||
T19019 | KMG-104AM | Others | |
KMG-104AM is a selective fluorescein-derived magnesium fluorescent membrane-permeable probe. It is successfully used to Intracellular 3D Mg2+ Imaging. |