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Search Results for " map3k "

12

Compounds

Cat No. Product Name Synonyms Targets
T60011 HS220 MAPK
HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.
T3350 Selonsertib GS-4997 Apoptosis , ASK , MAPK
Selonsertib (GS-4997) is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
T5190 GS-444217 GS 444217,GS444217 Apoptosis , ASK , MAPK
GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).
T3101 NQDI-1 NQDI1,NQDI 1 Apoptosis , ASK , MAPK
NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).
T5643 NG25 MAPK
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.
T9377 ASK1-IN-2 Apoptosis , ASK , MAPK
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
T3707 GNE-3511 GNE3511 DNA Alkylation , MAPK
GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.
T13099 TC ASK 10 ASK , MAPK
TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1)(IC50 of 14 nM).
T16987 TAO Kinase inhibitor 1 Others , MAPK
TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectiv...
T4264 Takinib EDHS-206 Apoptosis , MAPK
Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).
T14055 5Z-7-Oxozeaenol FR148083,L783279,LL-Z 1640-2 VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...
T69894 MAP3K14-IN-173
MAP3K14-IN-173 is a potent MAP3K14 kinase inhibitor.
TargetMol