leptin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39418	Leptin (93-105), human
	Leptin (93-105), human, refers to the peptide fragment consisting of amino acids 93 to 105 from the human leptin protein. Leptin is a peptide hormone comprising 167 amino acids, predominantly synthesized by adipocytes. I...
TP1356	Leptin (22-56), human
	Leptin(22-56),human is a peptide fragment of Leptin, which ACTS through a variety of subtypes of Ob-Rs.
T76221	Leptin (116-130)
	Leptin (116-130), a bioactive fragment of leptin, enhances synaptic plasticity in the hippocampus by promoting AMPA receptor trafficking to synapses. It preserves hippocampal synapse integrity and prevents neuronal cell ...
T7704	KY-226		Phosphatase
	KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)		Phosphatase
T2008	LY294002	LY 294002,NSC 697286,SF 1101	Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
	LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 ...		Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
T4079	LY-294002 hydrochloride	SF 1101,LY 294002,NSC 697286	PI3K
	LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation...		PI3K
T32645	Leptine I, from Solanum chacoense	Leptine I
	Leptine I, from Solanum chacoense is a glycoalkaloid in the foliage of the wild potato species Solanum chacoense.
TP1305	LEP(116-130)(mouse)		Others
	Leptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake an...		Others
TP1305L	LEP(116-130)(mouse)TFA(258276-95-8 free base)		Complement System
	LEP(116-130)(mouse) is a synthetic leptin peptide fragment.		Complement System
T23557	Talibegron hydrochloride	ZD2079 hydrochloride,ZD 2079	Adrenergic Receptor
	Talibegron hydrochloride (ZD2079 hydrochloride) is an β3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Relaxes rat mesenteric artery and isolated aorta in vitro. In...		Adrenergic Receptor
T81628	OB3
	OB3, a leptin derivative, exhibits greater efficacy than leptin in diminishing obesity and diabetes in mouse models. Additionally, OB3 mitigates leptin-associated inflammation and proliferation in hepatocellular carcinom...
T78020	Allo-aca
	Allo-aca, a leptin peptidomimetic, selectively inhibits leptin receptor activity as a potent antagonist peptide, effectively disrupting leptin signaling in various in vitro and in vivo models [1] [2].
T83145	Allo-aca TFA
	Allo-aca TFA, a potent and specific leptin receptor antagonist peptide, inhibits leptin signaling and function across various in vitro and in vivo models [1] [2].
T75899	CART(55-102)(human) TFA
	CART(55-102)(human) TFA, a human satiety factor, exhibits strong appetite-suppressing activity. It is closely linked with leptin and neuropeptide Y [1] [2].
TP2215	Agouti-related Protein (AGRP) (25-82), human		Others
	Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalam...		Others
T72745	Acipimox sodium	K-9321 sodium
	Acipimox (K-9321) sodium, a nicotinic acid analogue, functions as an antilipolytic agent by stimulating leptin release, inhibiting lipolysis, and reducing systemic free fatty acids (FFAs) levels, thereby enhancing insuli...
T71559	Melanotan II acetate
	Melanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases...
T75900	CART(55-102)(rat) TFA
	CART(55-102)(rat) TFA, a rat-derived satiety factor, exhibits potent appetite-suppressing properties. This compound is intricately linked to both leptin and neuropeptide Y, playing a crucial role in the regulation of hun...
T76366	CART (55-76), rat
	CART (55-76), rat, a neuropeptide comprising residues 55-76 of the CART peptide and serving as the N-terminal fragments of CART (55-102), functions as a rat satiety factor. It demonstrates potent appetite-suppressing act...
T76365	CART (1-39), Human, Rat
	CART (1-39), Human, Rat is a neuropeptide comprising the first 39 residues of the CART peptide. This compound serves as a rat satiety factor, possessing significant appetite-suppressing effects, and demonstrates a close ...