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Search Results for " lrp6 "

6

Compounds

Cat No. Product Name Synonyms Targets
T11571 HLY78 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine Wnt/beta-catenin
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.
T0906 Salinomycin Procoxacin Wnt/beta-catenin , Antibacterial
Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, specifically inhibits the growth of gram-positive bacteria. It acts as a potent inhibitor of Wnt/β-catenin signaling, blocking Wnt-induced LRP6 phosph...
T5342 IWP-O1 Wnt/beta-catenin , Porcupine
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
TN1103 Diphyllin ATPase , Proton pump , Influenza Virus , HIV Protease
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
TL0008 Gigantol Wnt/beta-catenin , Glucosidase
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...
TQ0215 Salinomycin sodium salt Sodium salinomycin,Salinomycin sodium Apoptosis , Wnt/beta-catenin , Antibacterial , Antibiotic , Autophagy
Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
TargetMol