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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T75535 | 5-epi-Arvestonate A | ||
5-epi-Arvestonate A, a sesquiterpenoid extracted from Seriphidium transiliense whole plants, enhances melanogenic production by stimulating MITF and tyrosinase family gene transcription. Additionally, it suppresses IFN-γ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4672 | Brevilin A | Apoptosis , Anti-infection , JAK , STAT , Autophagy | |
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si... | |||
T16324 | Nimbolide | Apoptosis , NF-κB , CDK | |
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene ... | |||
T5S1897 | Linderalactone | Apoptosis , Others , JAK | |
1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL. | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... |
Cat No. | Product Name | ||
---|---|---|---|
L3700 | JAK-STAT Compound Library | 256 compounds | |
A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening; |