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Search Results for " gpr40 "

20

Compounds

Cat No. Product Name Synonyms Targets
T11458 GPR40/FFAR1 modulator 1 GPR
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.
T15267 GPR40 agonist 4 Others
GPR40 agonist 4 is a potent free fatty acid agonist of receptor 1 (pEC50: 7.54).
T11457 GPR40 Activator 2 Others
GPR40 Activator 2 is a highly effective activator of the GPR40 receptor.
T11456 GPR40 Activator 1 Others
GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.
T11459 GPR40 agonist 1 Others
GPR40 agonist 1 is an effective new GPR40 agonist (EC50s: 17 nM and 2 nM for rGPR40 and hGPR40).
T10507 GPR40 Agonist 2 GPR
GPR40 Agonist 2 is a GPR40 agonist. It can be used in the research of diabetes.
T61055 GPR40 agonist 6
GPR40 agonist 6 (Compound 7a) is a potent and selective agonist of free fatty acid receptor 1 ( FFAR1 or GPR40 ) with an EC 50 of 0.058 μM against GPR40 [1].
T62542 GPR40 agonist 5
GPR40 agonist 5 is an orally active GPR40 (G protein-coupled receptor 40) agonist (EC50: 47 nM). gPR40 agonist 5 reduces blood glucose levels and improves glucose tolerance. gPR40 agonist 5 shows adequate control of hype...
TQ0020 AMG 837 calcium hydrate GPR
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM).
T1781 GW9508 GW 9508 GPR , Potassium Channel
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
T1286 Vincamine Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval GPR , Others
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.
T15810 LY2922470 GPR
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava...
T2351 Fasiglifam TAK875 GPR
Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist.
T60184 TUG-499 GPR , PPAR
TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors FFA2, FFA3 and the nuclear receptor PPARγ, as well as other di...
T7127 DC260126 Apoptosis , GPR
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
T22967 MEDICA16 MEDICA 16 GPR , Others , ATP Citrate Lyase
MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insu...
T12883 Fezagepras PBI-4050,Setogepram GPR
Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-proliferative actions.
T12375 Fezagepras sodium Setogepram sodium salt,PBI-4050 sodium salt GPR
Fezagepras sodium (Setogepram sodium salt) is an orally active GPR40 agonist and is an antagonist or inverse agonist for GPR84, with anti-fibrotic, anti-inflammatory and anti-proliferative actions.
T17177 TUG-424 TUG424 Others
TUG-424 significantly enhances glucose-stimulated insulin secretion at 100 nM. TUG-424 is a potent and selective free fatty acid receptor 1 agonist (EC50: 32 nM).
T14202 AM-4668 GPR
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.
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TargetMol