Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GPR40 agonist 4 is a potent free fatty acid agonist of receptor 1 (pEC50: 7.54).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 53.00 | |
5 mg | 5 days | $ 97.00 |
Description | GPR40 agonist 4 is a potent free fatty acid agonist of receptor 1 (pEC50: 7.54). |
Targets&IC50 | FFA1/GPR40:(pEC50)7.54 |
In vitro | GPR40 agonist 4 has a low risk of activating caspase-3/7. |
In vivo | The area under the curve of blood glucose (AUC0-120min) and blood insulin (AUC0-120min) reveal that the minimum effective dose of GPR40 agonist 4 is 3 mg/kg. The hyperglycemia state is also markedly improved in GPR40 agonist 4 (20 mg/kg) treated group. When GPR40 agonist 4 is dosed 60 min prior to the oral glucose challenge, single oral administration of GPR40 agonist 4 robustly decreases the plasma glucose excursion and enhances insulin secretion during an oral glucose tolerance test (OGTT) in a dose-dependent manner from 1 to 10 mg/kg. |
Molecular Weight | 416.87 |
Formula | C21H17ClO5S |
CAS No. | 2102196-57-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 160 mg/mL (383.81 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. More
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GPR40 agonist 4 2102196-57-4 Others GPR-40 agonist 4 inhibitor inhibit