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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11557 | FASN-IN-3 | Fatty Acid Synthase | |
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN). | |||
T11267 | FASN-IN-1 | TVB-2460 | Fatty Acid Synthase |
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatt... | |||
T15271 | Denifanstat | FASN-IN-2,TVB2640,TVB-2640 | Fatty Acid Synthase |
Denifanstat (FASN-IN-2) is a Fatty Acid Synthase (FASN) inhibitor(IC50 of 0.052 μM and an EC50 of 0.072 μM),with potential antineoplastic activity. | |||
T37776 | FASN-IN-4 tosylate | ||
FASN-IN-4 tosylate is a potent fatty acid synthase (FASN) inhibitor, exhibiting an IC50 value of 10 nM. Additionally, it demonstrates inhibitory activity against SARS-CoV-2, with an EC50 of 18.6 nM [2]. | |||
T11266 | FASN-IN-4 | FAS-IN-1 | Others |
FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM. | |||
T79416 | FASN-IN-6 | ||
FASN-IN-6 (compound 44), a potent fatty acid biosynthesis (FAB) inhibitor, serves as an antibacterial agent, exhibiting minimum inhibitory concentrations (MICs) of 1 μg/mL for S. aureus ATCC 25923 and 4 μg/mL for E. faec... | |||
T62925 | FASN-IN-5 | ||
FASN-IN-5 (example 11) is a FASN inhibitor that can be used in studies of TH17 or CSF1-mediated diseases or disorders (e.g. cancer, immune disorders, obesity). | |||
TQ0260 | Cerulenin | Antibiotic , Antifungal , Fatty Acid Synthase | |
Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus. | |||
T2824 | Pedunculoside | Others , Fatty Acid Synthase | |
Pedunculoside is extracted from Ilex rotunda Thunb. | |||
T7947 | FT113 | Fatty Acid Synthase | |
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity | |||
T0686 | Orlistat | Ro-18-0647,Tetrahydrolipstatin | Apoptosis , Others , Fatty Acid Synthase |
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor. | |||
T17180 | TVB-3166 | Apoptosis , Others , Fatty Acid Synthase | |
TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis,... | |||
T17181 | TVB-3664 | Fatty Acid Synthase | |
TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthe... | |||
T7798 | FGH10019 | FGH-10019 | NPC1L1 , Fatty Acid Synthase |
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM). | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
T5S0246 | Pseudoprotodioscin | Others , Fatty Acid Synthase | |
1. Pseudoprotodioscin has moderate cytotoxicity. | |||
TJS0387 | Desoxyrhaponticin | Deoxyrhapontin,Deoxyrhaponticin | Apoptosis , Fatty Acid Synthase |
1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least... | |||
T12437 | PF429242 dihydrochloride | S1P Receptor | |
PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM). | |||
T36841 | IPI-9119 | Fatty Acid Synthase | |
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM). | |||
T10656 | Trans-C75 | (±)-C75 | Others , Fatty Acid Synthase |
trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN). |