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FASN-IN-3

Catalog No. T11557 CAS 2097262-60-5

FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).

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FASN-IN-3, CAS 2097262-60-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).

In vitro

For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation.Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist.?Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 , results in secretion of IL-1 beta.?FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation.

Molecular Weight	384.47
Formula	C24H24N4O
CAS No.	2097262-60-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 33.33 mg/mL (86.69 mM), ultrasonic and warming and heat to 80°C

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Buckley, Douglas I, et al. HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS. US20170119786A1

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Metabolism Compound Library Lipid Metabolism Compound Library Inhibitor Library Anti-Metabolism Disease Compound Library Bioactive Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

FASN-IN-3 2097262-60-5 代谢 Fatty Acid Synthase Fatty Acid Synthase (FASN) Inhibitor inhibit FASNIN3 FASN IN 3 inhibitor

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