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Search Results for " faa "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T11256	FAAH inhibitor 1	Benzothiazole analog 3	FAAH
	FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.		FAAH
T67747	CB2R/FAAH modulator-3		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the ...		Cannabinoid Receptor , FAAH
T67896	CB2R/FAAH modulator-1		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the production of pro-inflammatory and anti-inflammatory cytokines and i...		Cannabinoid Receptor , FAAH
T67745	CB2R/FAAH modulator-2		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, an...		Cannabinoid Receptor , FAAH
T15268	FAAH-IN-2	O-Desmorpholinopropyl Gefitinib	FAAH , Autophagy
	FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).		FAAH , Autophagy
T63536	Dual FAAH/sEH-IN-1		FAAH , Epoxide Hydrolase
	Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.		FAAH , Epoxide Hydrolase
T11255	FAAH-IN-1		FAAH
	FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.		FAAH
T62558	FAAH-IN-5
	FAAH-IN-5 (Compound 7) is a relatively selective, irreversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50: 10.5 nM). FAAH-IN-5 has low PAMPA (parallel artificial membrane permeability assay) permeability.
T61707	FAAH/MAGL-IN-2
	FAAH/MAGL-IN-2, a potent and reversible inhibitor of FAAH and MAGL, demonstrates oral activity and the ability to cross the blood-brain barrier. It exhibits IC50 values of 11 nM for FAAH and 36 nM for MAGL (Ki values of ...
T73302	FAAH-IN-7
	FAAH-IN-7, a potent and reversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrates significant neuroprotective effects, particularly by mitigating oxidative stress in 1321N1 astrocytes. With an IC50 value of...
T61198	FAAH/MAGL-IN-1
	FAAH/MAGL-IN-1, also known as compound SIH 3, is a highly effective inhibitor of FAAH (fatty acid amide hydrolase) and MAGL (monoacylglycerol lipase). It exhibits IC50 values of 31 nM and 29 nM against FAAH and MAGL, res...
T62671	FAAH/MAGL-IN-3
	FAAH/MAGL-IN-3 (Compound 10) is an irreversible dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) that acts on FAAH (IC50: 179 nM) and MAGL (IC50: 759 nM). FAAH/MAGL-IN-3 showed littl...
T82421	FAAH/cPLA2α-IN-1		Phospholipase
	FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (IC50s) of 32 nM for FAAH and 47 nM for cPLA2α [1].		Phospholipase

Compounds

FAAH inhibitor 1

T11256

Synonym: Benzothiazole analog 3

Target: FAAH

CB2R/FAAH modulator-3

T67747

Synonym:

Target: Cannabinoid Receptor, FAAH

CB2R/FAAH modulator-1

T67896

Synonym:

Target: Cannabinoid Receptor, FAAH

CB2R/FAAH modulator-2

T67745

Synonym:

Target: Cannabinoid Receptor, FAAH

FAAH-IN-2

T15268

Synonym: O-Desmorpholinopropyl Gefitinib

Target: FAAH, Autophagy

Dual FAAH/sEH-IN-1

T63536

Synonym:

Target: FAAH, Epoxide Hydrolase

Target: Phospholipase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00876	FAH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. ...
TMPY-02544	FANCA Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h...
TMPY-05157	TGFBR2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
TMPK-00328	TGFBR2 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293 Cells
	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign...
TMPK-00329	TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated	Human	HEK293 Cells
	The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called sign...
TMPY-05810	TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated	Human	HEK293 Cells
	TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P37173.
TMPY-05508	TGFBR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TGFBR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is P37173.
TMPH-01325	FAAH2 Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatt...