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Search Results for " e-cadherin "

11

Compounds

Cat No. Product Name Synonyms Targets
T13410 ZLDI-8 Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.
T3144 BML-284 Wnt agonist 1 Wnt/beta-catenin
BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.
T8820 BML-284 hydrochloride BML-284 HCL,Wnt agonist 1 HCL Wnt/beta-catenin
BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
T4252 ML327 c-Myc , Autophagy
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
T81059 SWELYYPLRANL-NH2
SWELYYPLRANL-NH2 is a dual antagonist of E-cadherin and N-cadherin, effectively inhibiting the binding of phage clones to both E-cad/Fc and N-cad/Fc chimeric proteins with IC50 values of 0.7 μM and 0.09 μM, respectively....
T81058 SWELYYPLRANL-NH2 TFA
SWELYYPLRANL-NH2 TFA acts as an antagonist to both E-cadherin and N-cadherin, with inhibitory effects on phage clone binding to E- or N-cad/Fc chimeric proteins, exhibiting IC50 values of 0.7 μM and 0.09 μM, respectively...
T78532 HDAC-IN-55 Others
HDAC-IN-55(8j) is a small-molecule inhibitor that enhances E-cadherin expression and suppresses cancer cell proliferation [1].
T60639 SLEC-11
SLEC-11 emerged as a synthetic lethal(SL) lead in E-cadherin-deficient cells which has potential for the treatment of gastric cancer.
T41169 P21d hydrochloride
P21d hydrochloride is a potent and selective breast tumor Ki nase (Brk) inhibitor (IC50 = 30 nM). Exhibits >650-fold selectively for Brk over Aurora B Ki nase and Lck. Downregulates SNAIL protein, restores E-cadherin exp...
T62822 CT1-3
CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (...
T69685 AGPS-IN-2i MMP
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferat...
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