11
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13410 | ZLDI-8 | Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related | |
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein. | |||
T3144 | BML-284 | Wnt agonist 1 | Wnt/beta-catenin |
BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator. | |||
T8820 | BML-284 hydrochloride | BML-284 HCL,Wnt agonist 1 HCL | Wnt/beta-catenin |
BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor. | |||
T4252 | ML327 | c-Myc , Autophagy | |
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT). | |||
T81059 | SWELYYPLRANL-NH2 | ||
SWELYYPLRANL-NH2 is a dual antagonist of E-cadherin and N-cadherin, effectively inhibiting the binding of phage clones to both E-cad/Fc and N-cad/Fc chimeric proteins with IC50 values of 0.7 μM and 0.09 μM, respectively.... | |||
T81058 | SWELYYPLRANL-NH2 TFA | ||
SWELYYPLRANL-NH2 TFA acts as an antagonist to both E-cadherin and N-cadherin, with inhibitory effects on phage clone binding to E- or N-cad/Fc chimeric proteins, exhibiting IC50 values of 0.7 μM and 0.09 μM, respectively... | |||
T78532 | HDAC-IN-55 | Others | |
HDAC-IN-55(8j) is a small-molecule inhibitor that enhances E-cadherin expression and suppresses cancer cell proliferation [1]. | |||
T60639 | SLEC-11 | ||
SLEC-11 emerged as a synthetic lethal(SL) lead in E-cadherin-deficient cells which has potential for the treatment of gastric cancer. | |||
T41169 | P21d hydrochloride | ||
P21d hydrochloride is a potent and selective breast tumor Ki nase (Brk) inhibitor (IC50 = 30 nM). Exhibits >650-fold selectively for Brk over Aurora B Ki nase and Lck. Downregulates SNAIL protein, restores E-cadherin exp... | |||
T62822 | CT1-3 | ||
CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (... | |||
T69685 | AGPS-IN-2i | MMP | |
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferat... |