d2-like — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4007	Eticlopride hydrochloride		Dopamine Receptor
	Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).		Dopamine Receptor
T16392	ONC206		Dopamine Receptor
	ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and possesses broad-spectrum anti-tumor activity.		Dopamine Receptor
T14853	Cabergoline	FCE-21336	Dopamine Receptor , 5-HT Receptor , Autophagy
	Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal a...		Dopamine Receptor , 5-HT Receptor , Autophagy
T13164	Tipepidine hydrochloride		Potassium Channel , Dopamine Receptor
	Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.		Potassium Channel , Dopamine Receptor
T12899L	SEP-363856 hydrochloride	SEP-856 hydrochloride	Others , 5-HT Receptor
	SEP-363856 hydrochloride (SEP-856 hydrochloride) is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to trea...		Others , 5-HT Receptor
T23063	Nemonapride		Others
	Nemonapride is a dopamine D2-like receptor antagonist.		Others
T23381	Spiperone hydrochloride		Others
	5-HT2A serotonin and selective D2-like dopamine receptor antagonist		Others
T24696	Quinpirole dihydrochloride	(±)-Quinpirole dihydrochloride,LY-141865,Quinpirole 2HCl,LY 141865,(±)Quinpirole dihydrochloride
	Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.
T22493	2-CMDO		Others
	2-CMDO is a Dopamine D2-like receptor antagonist.		Others
T16857	SB269652		Others
	SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor.		Others
T10542	Bifeprunox		Others
	Bifeprunox is a potent partial agonist of dopamine D2-like and 5-HT1A receptor (pEC50: 6.37 for hippocampus 5-HT1A; pKis: 7.19 and 8.83 for cortex 5-HT1A and striatum D2). It is an antipsychotic for the research of schiz...		Others
T12899	SEP-363856	SEP-856	Others
	SEP-363856 is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to treatment of schizophrenia.		Others
T60501	Tipepidine
	Tipepidine is a non-narcotic antitussive with an antidepressant-like effect. Tipepidine reversibly inhibits dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK) ) (IC 50 = 7.0 μM) and subsequently activates VTA do...
T60418	Ropinirole
	Ropinirole (SKF 101468) is a selective D2-like family receptor agonist whereas it has no affinity for the D1 receptors. It is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor, which als...
T74230	Dioleoylphosphatidylglycerol
	Dioleoylphosphatidylglycerol (DOPG), a naturally occurring phospholipid, is synthesized through the action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). It functions to suppress the production of inflammatory mediat...
T63405	NAZ2329
	NAZ2329 is the first cell-permeable inhibitor of the R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), which is a variant and preferentially inhibits PTPRZ (IC50=7.5 μM for hPTPRZ1) and PTPRG (IC50=4.8...