Search Result

Search Results for " cxcl10 "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T10297L	AMG 487		CXCR
	AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.		CXCR
T1781	GW9508	GW 9508	GPR , Potassium Channel
	GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.		GPR , Potassium Channel
T76741	Eldelumab	BMS-936557,MDX-1100	CXCR
	Eldelumab (BMS-936557) is a humanized anti-IP-10 IgG type 1 monoclonal antibody with inhibitory activity against CXCL10.Eldelumab has anti-inflammatory activity and selectively binds to CXCL10 and can be used in the stud...		CXCR
T73322	TBK1-IN-1		IκB/IKK
	TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.		IκB/IKK
TP2035	FSL-1	FSL 1
	TLR2/6 agonist (also a putative TLR10 ligand). Activates NF-κB. Induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. Synergizes with IFNγ to induce CXCL10 release from melanoma cells.
T72970	Rosolic Acid
	Rosolic Acid serves as an Nrf2 activator and influences its downstream targets, enhancing angiogenic factor levels while reducing inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). This compound not ...
T38160	STING Agonist 1a
	STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expres...
T83841	STING Agonist D61	D61,Stimulator of Interferon Genes Agonist D61
	STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline phosphatase (SEAP) and IFN-β-inducible reporter genes in cellular as...
T36461	CAY10748	CAY10748
	CAY10748 is an agonist of stimulator of interferon genes (STING; IC50= 0.3794 μM in a competition binding assay).1It activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 μM, re...
T83775	STING Agonist 12L	Stimulator of Interferon Genes Agonist 12L
	STING agonist 12L is a stimulator of interferon genes (STING) agonist that exhibits binding affinity for both wild-type STING and its variants R232, AQ, and Q with half-maximal inhibitory concentrations (IC50s) of 1.15 µ...
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...

Compounds

Target: GPR, Potassium Channel

Eldelumab

T76741

Synonym: BMS-936557,MDX-1100

Synonym: D61,Stimulator of Interferon Genes Agonist D61

Synonym: Stimulator of Interferon Genes Agonist 12L

Target:

β-Defensin-3 (human) (trifluoroacetate salt)

T35452

Synonym:

Target:

β-Defensin-4 (human) (trifluoroacetate salt)

T35453

Synonym:

Target:

β-Defensin-2 (human) (trifluoroacetate salt)

T35451

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02970	CXCL10 Protein, Human, Recombinant	Human	E. coli
	CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778.
TMPK-01269	CXCL10 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel...
TMPJ-00008	CXCL10 Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX...
TMPY-04943	CXCL10 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	CXCL10 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10 kDa and the accession number is P48973.
TMPY-03274	CXCL11 Protein, Human, Recombinant	Human	E. coli
	I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low e...
TMPH-02612	CXCR3 Protein, Mouse, Recombinant (His & KSI)	Mouse	E. coli
	Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell c...
TMPJ-00884	CXCL9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor foun...
TMPJ-01084	CXCL9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b...
TMPY-00176	FNDC4 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of F...