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Search Results for " ctla-1 "

Targets

11

Compounds

1807

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3189 B7/CD28 interaction inhibitor 1 CTLA-4 inhibitor Others
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.
T81329 Quavonlimab MK-1308
Quavonlimab (MK-1308) is a novel antibody targeting CTLA-4 [1].
T77103 Nurulimab
Nurulimab (BCD-145) is a humanized monoclonal antibody targeting cytotoxic T lymphocyte antigen-4 (anti-CTLA-4). It has potential applications in melanoma research [1].
T76728 Vudalimab
Vudalimab, a fully humanized bispecific monoclonal antibody, effectively inhibits both PD-1 and CTLA-4 immune checkpoint receptors. This dual action facilitates the selective activation of T-cells targeting tumors.
T77072 Lorigerlimab
Lorigerlimab (MGD019) is a bispecific IgG4 dual-affinity re-targeting (DART) antibody that blocks both PD-1 and CTLA-4, enhancing T-cell responses. It is under investigation for the treatment of metastatic castration-res...
T80598 Davoceticept CD80 vIgD-Fc,ALPN-202
Davoceticept (ALPN-202; CD80 vIgD-Fc), a monoclonal antibody that targets CTLA-4, is comprised of the (1-107) fragment of CD80 fused to the IGHG1 Fc domain through a peptidyl linker. It is commonly produced in CHO (Chine...
T82268 Gotistobart BNT 316,ONC-392
Gotistobart (ONC-392) is a humanized anti-CTLA-4 antibody that enhances immunotherapy by selectively depleting regulatory T cells (Treg) within the tumor microenvironment [1].
T76968 Tuvonralimab
Tuvonralimab (PSB-205; QL1706), comprising a combination of Iparomlimab and Tuvonralimab [1], functions as a dual immune checkpoint inhibitor through its formulation of anti-PD-1 IgG4 and anti-CTLA-4 IgG1 antibodies.
T81124 Sovipostobart
Sovipostobart, an immunoglobulin G1-kappa monoclonal antibody targeting CTLA-4 in Homo sapiens, features a cleavable prodomain. This compound serves as both an immunostimulant and antineoplastic [1].
T76859 Bavunalimab
Bavunalimab (Anti-Human CTLA4xLAG3), a bispecific human monoclonal antibody targeting CTLA-4 and LAG-3, activates T cells in NSG mice and is utilized in cancer research [1].
T76933 Botensilimab
Botensilimab (AGEN 1181), a humanized monoclonal antibody targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4), functions as an activator of both innate and adaptive immunity. It is currently being researched for its pote...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05159 Granzyme A/GZMA Protein, Human, Recombinant (His) Human HEK293
Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 cells.
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His) Human HEK293
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His) Mouse Human Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPJ-00555 B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T...
TMPY-00818 Granzyme H/GZMH Protein, Human, Recombinant (His) Human HEK293
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes...
TMPJ-00556 B7-2 Protein, Human, Recombinant (His) Human Human Cells
The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T...
TMPY-02473 ICOS Protein, Mouse, Recombinant (hFc) Mouse HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-05156 ICOS Protein, Human, Recombinant (rFc) Human HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His) Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-04824 CTLA-4 Protein, Human, Recombinant Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-00674 B7-1 Protein, Human, Recombinant Human HEK293
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B c...
TMPY-05079 PD-1 Protein, Human, Recombinant (mFc) Human HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-00996 PD-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05395 PD-1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-04898 PD-1 Protein, Human, Recombinant (hFc) Human HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05815 PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated Canine HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-00897 PD-1 Protein, Human, Recombinant (His) Human HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-04342 PD-1 Protein, Canine, Recombinant (His) Canine HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-05260 PD-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Programmed cell death 1, also known as PDCD1, is a type I transmembrane glycoprotein, and is an immunoreceptor belonging to the CD28/CTLA-4 family negatively regulates antigen receptor signaling by recruiting protein tyr...
TMPY-01604 CTLA-4 Protein, Mouse, Recombinant (His) Mouse HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPK-00179 B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated Human HEK293
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligan...
TMPK-00178 B7-1 Protein, Human, Recombinant (His & Avi) Human HEK293
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligan...
TMPY-03311 ICOS Protein, Rat, Recombinant (hFc) Rat HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPK-00882 B7-2 Protein, Human, Recombinant (hFc) Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00880 B7-2 Protein, Human, Recombinant (His & Avi) Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00881 B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPK-00086 ICOS Protein, Human, Recombinant (aa 21-134, His) Human HEK293
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. ...
TMPK-00087 ICOS Protein, Human, Recombinant (C136S & C137S, His) Human HEK293
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. ...
TMPY-04991 ICOS Protein, Mouse, Recombinant (rFc) Mouse HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-06979 ICOS Protein, Human, Recombinant (His) Human HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPJ-00640 CTLA-4 Protein, Cavia porcellus, Recombinant (His) Cavia porcellus P. pastoris
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPJ-00635 CTLA-4 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPJ-00636 CTLA-4 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPY-01399 ICOS Protein, Human, Recombinant (His & hFc) Human HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-06209 ICOS Protein, Mouse, Recombinant (His) Mouse HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-05651 ICOS Protein, Mouse, Recombinant (hFc & Avi), Biotinylated Mouse HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-00461 BTLA Protein, Rat, Recombinant (mFc) Rat HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-05645 ICOS Protein, Rhesus, Recombinant (hFc & Avi), Biotinylated Rhesus HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-05174 ICOS Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-05389 ICOS Protein, Human, Recombinant (hFc) Human HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPJ-00958 B7-1 Protein, Rabbit, Recombinant (His) Rabbit Human Cells
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their recep...
TMPJ-00107 CTLA-4 Protein, Human, Recombinant (Flag) Human Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence...
TMPJ-00108 CTLA-4 Protein, Human, Recombinant (GST) Human Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence...
TMPK-00653 B7-2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti...
TMPJ-00630 B7-1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus Human Cells
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and...
TMPY-06913 BTLA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-06922 BTLA Protein, Human, Recombinant (isoform1, His) Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-00175 BTLA Protein, Human, Recombinant (hFc) Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-06711 B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B c...
TMPY-05811 B7-1 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B c...
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Granzyme A/GZMA Protein, Human, Recombinant (His)
TMPY-05159
Species: Human
Expression System: HEK293
Granzyme B/GZMB Protein, Human, Recombinant (His)
TMPY-00817
Species: Human
Expression System: HEK293
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
TMPJ-00770
Species: Mouse
Expression System: Human Cells
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00555
Species: Human
Expression System: Human Cells
Granzyme H/GZMH Protein, Human, Recombinant (His)
TMPY-00818
Species: Human
Expression System: HEK293
B7-2 Protein, Human, Recombinant (His)
TMPJ-00556
Species: Human
Expression System: Human Cells
ICOS Protein, Mouse, Recombinant (hFc)
TMPY-02473
Species: Mouse
Expression System: HEK293
ICOS Protein, Human, Recombinant (rFc)
TMPY-05156
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant
TMPY-04824
Species: Human
Expression System: HEK293
B7-1 Protein, Human, Recombinant
TMPY-00674
Species: Human
Expression System: HEK293
PD-1 Protein, Human, Recombinant (mFc)
TMPY-05079
Species: Human
Expression System: HEK293
PD-1 Protein, Mouse, Recombinant (His)
TMPY-00996
Species: Mouse
Expression System: HEK293
PD-1 Protein, Mouse, Recombinant (hFc)
TMPY-05395
Species: Mouse
Expression System: HEK293
PD-1 Protein, Human, Recombinant (hFc)
TMPY-04898
Species: Human
Expression System: HEK293
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated
TMPY-05815
Species: Canine
Expression System: HEK293
PD-1 Protein, Human, Recombinant (His)
TMPY-00897
Species: Human
Expression System: HEK293
PD-1 Protein, Canine, Recombinant (His)
TMPY-04342
Species: Canine
Expression System: HEK293
PD-1 Protein, Cynomolgus, Recombinant (His)
TMPY-05260
Species: Cynomolgus
Expression System: HEK293
CTLA-4 Protein, Mouse, Recombinant (His)
TMPY-01604
Species: Mouse
Expression System: HEK293
B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated
TMPK-00179
Species: Human
Expression System: HEK293
B7-1 Protein, Human, Recombinant (His & Avi)
TMPK-00178
Species: Human
Expression System: HEK293
ICOS Protein, Rat, Recombinant (hFc)
TMPY-03311
Species: Rat
Expression System: HEK293
B7-2 Protein, Human, Recombinant (hFc)
TMPK-00882
Species: Human
Expression System: HEK293
B7-2 Protein, Human, Recombinant (His & Avi)
TMPK-00880
Species: Human
Expression System: HEK293
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00881
Species: Human
Expression System: HEK293
ICOS Protein, Human, Recombinant (aa 21-134, His)
TMPK-00086
Species: Human
Expression System: HEK293
ICOS Protein, Human, Recombinant (C136S & C137S, His)
TMPK-00087
Species: Human
Expression System: HEK293
ICOS Protein, Mouse, Recombinant (rFc)
TMPY-04991
Species: Mouse
Expression System: HEK293
ICOS Protein, Human, Recombinant (His)
TMPY-06979
Species: Human
Expression System: HEK293
CTLA-4 Protein, Cavia porcellus, Recombinant (His)
TMPJ-00640
Species: Cavia porcellus
Expression System: P. pastoris
CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00635
Species: Cynomolgus
Expression System: Human Cells
CTLA-4 Protein, Cynomolgus, Recombinant (His)
TMPJ-00636
Species: Cynomolgus
Expression System: Human Cells
ICOS Protein, Human, Recombinant (His & hFc)
TMPY-01399
Species: Human
Expression System: HEK293
ICOS Protein, Mouse, Recombinant (His)
TMPY-06209
Species: Mouse
Expression System: HEK293
ICOS Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
TMPY-05651
Species: Mouse
Expression System: HEK293
BTLA Protein, Rat, Recombinant (mFc)
TMPY-00461
Species: Rat
Expression System: HEK293
ICOS Protein, Rhesus, Recombinant (hFc & Avi), Biotinylated
TMPY-05645
Species: Rhesus
Expression System: HEK293
ICOS Protein, Rhesus, Recombinant (hFc)
TMPY-05174
Species: Rhesus
Expression System: HEK293
ICOS Protein, Human, Recombinant (hFc)
TMPY-05389
Species: Human
Expression System: HEK293
B7-1 Protein, Rabbit, Recombinant (His)
TMPJ-00958
Species: Rabbit
Expression System: Human Cells
CTLA-4 Protein, Human, Recombinant (Flag)
TMPJ-00107
Species: Human
Expression System: Human Cells
CTLA-4 Protein, Human, Recombinant (GST)
TMPJ-00108
Species: Human
Expression System: Human Cells
B7-2 Protein, Cynomolgus, Recombinant (His)
TMPK-00653
Species: Cynomolgus
Expression System: HEK293
B7-1 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00630
Species: Cynomolgus
Expression System: Human Cells
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06913
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (isoform1, His)
TMPY-06922
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (hFc)
TMPY-00175
Species: Human
Expression System: HEK293
B7-1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06711
Species: Mouse
Expression System: HEK293
B7-1 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05811
Species: Mouse
Expression System: HEK293
TargetMol