csf-1r-in-2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13194	CSF1R-IN-2		c-Fms , c-Met/HGFR , Src
	CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).		c-Fms , c-Met/HGFR , Src
T2624	OSI-930	OSI 930	Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
	OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T10644	C-Fms-IN-10		Others
	c-Fms-IN-10 is the derivative of thieno [3,2-d] pyrimidine, a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.		Others
T76868	Lacnotuzumab
	Lacnotuzumab (MCS110), a humanized IgG1/κ monoclonal antibody, neutralizes and inhibits the interaction between CSF-1 and its receptor, CSF-1R. It is utilized in researching pigmented villonodular synovitis [1] [2].
T76915	Axatilimab
	Axatilimab (SNDX-6352), a humanized IgG4 antibody that binds with high affinity to CSF-1R, is utilized in the study of chronic graft versus host disease (cGVHD) and various neoplastic diseases [1] [2].